Curation Details
Interaction ID: MINT-15522

Unique identifier for interactor Auniprotkb:P15172
Unique identifier for interactor Buniprotkb:P11831
Alternative identifier for interactor Aintact:EBI-488878
uniprotkb:O75321
ensembl:ENSP00000250003.3
Alternative identifier for interactor Bintact:EBI-493034
uniprotkb:Q5T648
intact:EBI-28988887
ensembl:ENSP00000265354.4
Aliases for Apsi-mi:myod1_human(display_long)
uniprotkb:Myogenic factor 3(gene name synonym)
uniprotkb:MYOD1(gene name)
psi-mi:MYOD1(display_short)
uniprotkb:MYF3(gene name synonym)
uniprotkb:MYOD(gene name synonym)
uniprotkb:BHLHC1(gene name synonym)
uniprotkb:Class C basic helix-loop-helix protein 1(gene name synonym)
Aliases for Bpsi-mi:srf_human(display_long)
uniprotkb:SRF(gene name)
psi-mi:SRF(display_short)
Interaction detection methodspsi-mi:"MI:0018"(two hybrid)
First authorGroisman et al. (1996)
Identifier of the publicationpubmed:8617811
mint:MINT-5220973
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8674600
mint:MINT-15522
Confidence scoreintact-miscore:0.53
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:No complex could be detected between MyoD and SRF in the absence of E12. A likely interpretation of this result is that heterodimeric formation between E12 and MyoD induces a conformational change in the proteins thatunmasks a site of interaction with SRF
comment:homomint
comment:mint
NCBI Taxonomy identifier for the host organismtaxid:-4(in vivo)
taxid:-4(in vivo)
Parameters of the interaction-
Creation date2002/10/17
Update date2024/09/10
negative Boolean valuefalse
Feature(s) for interactor Atag:?-?(MINT-1516145)
Feature(s) for interactor Btag:?-?(MINT-1516139)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification