Curation Details
Interaction ID: MINT-14323

Unique identifier for interactor Auniprotkb:O43524
Unique identifier for interactor Buniprotkb:P63104
Alternative identifier for interactor Aintact:EBI-1644164
uniprotkb:Q9BZ04
uniprotkb:O15171
uniprotkb:Q5T2I7
ensembl:ENSP00000339527.6
ensembl:ENSP00000385824.1
uniprotkb:E1P5E6
uniprotkb:B4DVZ6
Alternative identifier for interactor Bintact:EBI-347088
uniprotkb:P29213
uniprotkb:P29312
uniprotkb:Q32P43
uniprotkb:Q5XJ08
uniprotkb:Q6GPI2
uniprotkb:Q6IN74
uniprotkb:Q6NUR9
uniprotkb:Q6P3U9
uniprotkb:Q86V33
uniprotkb:A8K1N0
uniprotkb:B7Z465
ensembl:ENSP00000309503.3
ensembl:ENSP00000379281.3
ensembl:ENSP00000379283.2
ensembl:ENSP00000379286.3
ensembl:ENSP00000379287.2
ensembl:ENSP00000379288.2
ensembl:ENSP00000395114.2
ensembl:ENSP00000398599.1
Aliases for Apsi-mi:foxo3_human(display_long)
uniprotkb:FOXO3(gene name)
psi-mi:FOXO3(display_short)
uniprotkb:FKHRL1(gene name synonym)
uniprotkb:FOXO3A(gene name synonym)
uniprotkb:Forkhead in rhabdomyosarcoma-like 1(gene name synonym)
uniprotkb:AF6q21 protein(gene name synonym)
Aliases for Bpsi-mi:1433z_human(display_long)
uniprotkb:YWHAZ(gene name)
psi-mi:YWHAZ(display_short)
uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorBrunet et al. (1999)
Identifier of the publicationpubmed:10102273
mint:MINT-5211323
imex:IM-27311
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-6970409
mint:MINT-14323
imex:IM-27311-1
Confidence scoreintact-miscore:0.85
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:Fig. 4
comment:Mutagenesis to alanine of the threo32 or ser253 abolish binding
comment:homomint
comment:domino
comment:mint
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293t)
taxid:9606(Homo sapiens HEK293T embryonic kidney cell)
Parameters of the interaction-
Creation date2003/01/20
Update date2024/09/10
negative Boolean valuefalse
Feature(s) for interactor Amutation decreasing interaction strength:32-32(MINT-365929)
mutation decreasing interaction strength:253-253(MINT-365931)
ha tag:?-?
mutation with no effect:315-315
mutation disrupting interaction strength:32-32,253-253
Feature(s) for interactor Bflag tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot