Curation Details
Interaction ID: MINT-14025

Unique identifier for interactor Auniprotkb:P37088
Unique identifier for interactor Buniprotkb:P46934
Alternative identifier for interactor Aintact:EBI-7845444
intact:MINT-198663
uniprotkb:O43271
uniprotkb:Q9UM64
uniprotkb:C5HTZ0
uniprotkb:B4E2Q5
uniprotkb:A5X2U9
uniprotkb:Q6GSQ6
ensembl:ENSP00000228916.2
Alternative identifier for interactor Bintact:EBI-726944
uniprotkb:A1KY35
uniprotkb:A6ND72
uniprotkb:A7MD29
uniprotkb:B4E2R7
uniprotkb:B7ZM59
uniprotkb:B7ZM60
uniprotkb:B9EGN5
uniprotkb:D6RF89
intact:EBI-28969445
ensembl:ENSP00000424827.1
Aliases for Apsi-mi:scnna_human(display_long)
uniprotkb:SCNN1A(gene name)
psi-mi:SCNN1A(display_short)
uniprotkb:SCNN1(gene name synonym)
uniprotkb:"Epithelial Na(+) channel subunit alpha"(gene name synonym)
uniprotkb:Nonvoltage-gated sodium channel 1 subunit alpha(gene name synonym)
uniprotkb:SCNEA(gene name synonym)
uniprotkb:Alpha-NaCH(gene name synonym)
Aliases for Bpsi-mi:nedd4_human(display_long)
uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)
uniprotkb:NEDD4(gene name)
psi-mi:NEDD4(display_short)
uniprotkb:KIAA0093(gene name synonym)
uniprotkb:NEDD4-1(gene name synonym)
uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)
uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym)
uniprotkb:RPF1(gene name synonym)
uniprotkb:PIG53(orf name)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorSnyder et al. (2001)
Identifier of the publicationpubmed:11359767
mint:MINT-5214035
imex:IM-28177
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7845574
mint:MINT-14025
imex:IM-28177-7
Confidence scoreintact-miscore:0.68
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:Fig. 5
comment:homomint
comment:mint
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2002/04/12
Update date2022/01/25
negative Boolean valuefalse
Feature(s) for interactor Aflag tag:?-?
Feature(s) for interactor Bmutation with no effect:631-631,629-629
mutation with no effect:911-911,913-913
mutation with no effect:629-629,631-631,786-786,788-788,911-911,913-913
mutation disrupting interaction strength:631-631,786-786,629-629,788-788,859-859,861-861
mutation with no effect:786-786,788-788
mutation disrupting interaction strength:861-861,859-859
mutation disrupting interaction strength:629-629,631-631,786-786,788-788,859-859,861-861,911-911,913-913
mutation disrupting interaction strength:786-786,788-788,859-859,861-861,911-911,913-913
mutation disrupting interaction strength:629-629,631-631,859-859,861-861,911-911,913-913
35s radiolabel:?-?
binding-associated region:114-927(MINT-577716)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AMolecular weight estimation by autoradiography
Participant identification method for interactor BMolecular weight estimation by autoradiography