Curation Details
Interaction ID: MINT-13742

Unique identifier for interactor Auniprotkb:O96017
Unique identifier for interactor Buniprotkb:P04637
Alternative identifier for interactor Aintact:EBI-1180783
uniprotkb:B7ZBF3
uniprotkb:B7ZBF4
uniprotkb:B7ZBF5
uniprotkb:Q9HBS5
uniprotkb:A8K3Y9
ensembl:ENSP00000385747.1
ensembl:ENSP00000386087.1
ensembl:ENSP00000497000.1
uniprotkb:Q6QA03
uniprotkb:Q6QA04
uniprotkb:Q6QA05
uniprotkb:Q6QA06
uniprotkb:Q6QA07
uniprotkb:Q6QA08
uniprotkb:Q6QA10
uniprotkb:Q6QA11
uniprotkb:Q6QA12
uniprotkb:Q6QA13
uniprotkb:Q9HCQ8
uniprotkb:Q9UGF0
uniprotkb:Q9UGF1
Alternative identifier for interactor Bintact:EBI-366083
uniprotkb:Q2XN98
uniprotkb:Q3LRW1
uniprotkb:Q3LRW2
uniprotkb:Q3LRW3
uniprotkb:Q3LRW4
uniprotkb:Q3LRW5
uniprotkb:Q15086
uniprotkb:Q15087
uniprotkb:Q15088
uniprotkb:Q16535
uniprotkb:Q16807
uniprotkb:Q16808
uniprotkb:Q16809
uniprotkb:Q16810
uniprotkb:Q16811
uniprotkb:Q16848
uniprotkb:Q86UG1
uniprotkb:Q8J016
uniprotkb:Q99659
uniprotkb:Q9BTM4
uniprotkb:Q9HAQ8
uniprotkb:Q9NP68
uniprotkb:Q9NPJ2
uniprotkb:Q9NZD0
uniprotkb:Q9UBI2
uniprotkb:Q9UQ61
ensembl:ENSP00000269305.4
ensembl:ENSP00000391478.2
ensembl:ENSP00000424104.2
ensembl:ENSP00000426252.2
intact:EBI-28980681
Aliases for Apsi-mi:chk2_human(display_long)
uniprotkb:CHEK2(gene name)
psi-mi:CHEK2(display_short)
uniprotkb:CHK2(gene name synonym)
uniprotkb:RAD53(gene name synonym)
uniprotkb:Cds1 homolog(gene name synonym)
uniprotkb:Checkpoint kinase 2(gene name synonym)
uniprotkb:CDS1(gene name synonym)
uniprotkb:CHK2 checkpoint homolog(gene name synonym)
Aliases for Bpsi-mi:p53_human(display_long)
uniprotkb:TP53(gene name)
psi-mi:TP53(display_short)
uniprotkb:P53(gene name synonym)
uniprotkb:Tumor suppressor p53(gene name synonym)
uniprotkb:Phosphoprotein p53(gene name synonym)
uniprotkb:Antigen NY-CO-13(gene name synonym)
Interaction detection methodspsi-mi:"MI:0045"(experimental interaction detection)
First authorLee et al. (2000)
Identifier of the publicationpubmed:10724175
mint:MINT-5212334
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7227367
mint:MINT-13742
Confidence scoreintact-miscore:0.65
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:NFA
comment:If p53 is phosphorylated on Ser20, preformed complexes Mdm2/p53 are dissociated and p53 does not bind Mdm2
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:-4(in vivo)
taxid:-4(in vivo)
Parameters of the interaction-
Creation date2002/04/19
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification