Curation Details
Interaction ID: MINT-13689

Unique identifier for interactor Auniprotkb:P68254
Unique identifier for interactor Buniprotkb:Q61337
Alternative identifier for interactor Aintact:EBI-400675
uniprotkb:P35216
uniprotkb:Q3TW69
uniprotkb:Q3UJN5
uniprotkb:Q5SP76
uniprotkb:Q5U423
uniprotkb:Q66JR6
ensembl:ENSMUSP00000100067.2
ensembl:ENSMUSP00000123605.3
Alternative identifier for interactor Bintact:EBI-400328
ensembl:ENSMUSP00000025910.6
Aliases for Apsi-mi:1433t_mouse(display_long)
uniprotkb:Ywhaq(gene name)
psi-mi:Ywhaq(display_short)
uniprotkb:14-3-3 protein tau(gene name synonym)
Aliases for Bpsi-mi:bad_mouse(display_long)
uniprotkb:Bad(gene name)
psi-mi:Bad(display_short)
uniprotkb:Bbc6(gene name synonym)
uniprotkb:Bcl-2-binding component 6(gene name synonym)
uniprotkb:Bcl-xL/Bcl-2-associated death promoter(gene name synonym)
uniprotkb:Bcl2 antagonist of cell death(gene name synonym)
Interaction detection methodspsi-mi:"MI:0019"(coimmunoprecipitation)
First authorZha et al. (1996)
Identifier of the publicationmint:MINT-5221233
pubmed:8929531
NCBI Taxonomy identifier for interactor Ataxid:10090(mouse)
taxid:10090(Mus musculus)
NCBI Taxonomy identifier for interactor Btaxid:10090(mouse)
taxid:10090(Mus musculus)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8663590
mint:MINT-13689
Confidence scoreintact-miscore:0.53
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:"\"- screening in expression cloning with BAD-GST with Heart Muscle Kinase domain p32 labeled screening an embryonic mouse library , 14-3-3 TAUrn- CoIP with anti BAD, western with anti 14-3-3. In FL5.12, overexpression of BAD and HA-14-3-3rn- Alanine scanning in CoIP overexpressing BAD and HA-14-3-3: each ser can singularly bind 14-3-3rn- When ser mutated bad is expressed, cell die because they interact BAD-Bcl-XLrn\""
comment:domino
comment:mint
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:-4(in vivo)
taxid:-4(in vivo)
Parameters of the interaction-
Creation date2003/01/21
Update date2025/08/07
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor BO-phospho-L-serine:112-112(MINT-1520462)
O-phospho-L-serine:136-136(MINT-1520460)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant