Curation Details
Interaction ID: IM-30520-1

Unique identifier for interactor Auniprotkb:P48023
Unique identifier for interactor Buniprotkb:O15519
Alternative identifier for interactor Aintact:EBI-495538
uniprotkb:Q9BZP9
ensembl:ENSP00000356694.2
Alternative identifier for interactor Bintact:EBI-514941
uniprotkb:Q53TS6
uniprotkb:O14673
uniprotkb:O14674
uniprotkb:O14675
uniprotkb:O15137
uniprotkb:O15138
uniprotkb:O15356
uniprotkb:O15510
uniprotkb:O43618
uniprotkb:O43619
uniprotkb:O43620
uniprotkb:O60458
uniprotkb:O60459
uniprotkb:Q96TE4
uniprotkb:Q9UEW1
uniprotkb:Q54AF1
uniprotkb:B7Z9F9
uniprotkb:B4DJE0
ensembl:ENSP00000312455.2
ensembl:ENSP00000399420.2
Aliases for Apsi-mi:tnfl6_human(display_long)
uniprotkb:Fas antigen ligand(gene name synonym)
uniprotkb:CD95L(gene name synonym)
uniprotkb:Apoptosis antigen ligand(gene name synonym)
uniprotkb:FASLG(gene name)
psi-mi:FASLG(display_short)
uniprotkb:APT1LG1(gene name synonym)
uniprotkb:FASL(gene name synonym)
uniprotkb:TNFSF6(gene name synonym)
uniprotkb:CD95 ligand(gene name synonym)
Aliases for Bpsi-mi:cflar_human(display_long)
uniprotkb:Cellular FLICE-like inhibitory protein(gene name synonym)
uniprotkb:Caspase-eight-related protein(gene name synonym)
uniprotkb:Caspase-like apoptosis regulatory protein(gene name synonym)
uniprotkb:MACH-related inducer of toxicity(gene name synonym)
uniprotkb:Caspase homolog(gene name synonym)
uniprotkb:Inhibitor of FLICE(gene name synonym)
uniprotkb:FADD-like antiapoptotic molecule 1(gene name synonym)
uniprotkb:Usurpin(gene name synonym)
uniprotkb:CFLAR(gene name)
psi-mi:CFLAR(display_short)
uniprotkb:CASH(gene name synonym)
uniprotkb:CLARP(gene name synonym)
uniprotkb:MRIT(gene name synonym)
uniprotkb:CASP8AP1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorGalenkamp et al. (2014)
Identifier of the publicationpubmed:25890358
imex:IM-30520
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-16640663
imex:IM-30520-1
Confidence scoreintact-miscore:0.35
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f3b
agonist:"\"TNFA (P01375)\""
curation depth:imex curation
dataset:Cancer - Interactions investigated in the context of cancer
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-sk-n-as)
taxid:9606(Homo sapiens SK-N-AS neuroblatoma cell)
Parameters of the interaction-
Creation date2017/12/01
Update date2025/12/28
negative Boolean valuefalse
Feature(s) for interactor Afc-igg tag:?-?
sufficient binding region:139-281
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot