| Unique identifier for interactor A | uniprotkb:P18247 |
| Unique identifier for interactor B | uniprotkb:P06730 |
| Alternative identifier for interactor A | intact:EBI-66896638 uniprotkb:Q85266 uniprotkb:Q85267 uniprotkb:Q85268 uniprotkb:Q85269 uniprotkb:Q85270 uniprotkb:Q85271 uniprotkb:Q85272 uniprotkb:Q85273 |
| Alternative identifier for interactor B | intact:EBI-73440 uniprotkb:Q96E95 uniprotkb:D6RCQ6 uniprotkb:B7Z6V1 ensembl:ENSP00000389624.2 intact:EBI-28969298 |
| Aliases for A | psi-mi:polg_pvyn(display_long) |
| Aliases for B | psi-mi:if4e_human(display_long) uniprotkb:mRNA cap-binding protein(gene name synonym) uniprotkb:eIF-4F 25 kDa subunit(gene name synonym) uniprotkb:EIF4E(gene name) psi-mi:EIF4E(display_short) uniprotkb:EIF4EL1(gene name synonym) uniprotkb:EIF4F(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Coutinho et al. (2019) |
| Identifier of the publication | pubmed:31712417 imex:IM-30417 |
| NCBI Taxonomy identifier for interactor A | taxid:12219(PVY) taxid:12219("Potato virus Y (strain N)") |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0914"(association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-66897630 imex:IM-30417-13 |
| Confidence score | intact-miscore:0.67 |
| Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:fig. 6d comment:We observed that VPg–FLAG immunoprecipitated with endogenous eIF4E, endogenous eIF4G, and the RNA helicase DDX3, which is part of the active translation complex, but not with 4E-BP1, the inhibitor of eIF4E. Thus, VPg engaged active translation initiation complexes. curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-u2os) taxid:9606(Homo sapiens U2OS osteosarcoma cell) |
| Parameters of the interaction | - |
| Creation date | 2025/07/09 |
| Update date | 2025/08/13 |
| negative Boolean value | false |
| Feature(s) for interactor A | flag tag:?-? |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Anti tag western blot |
| Participant identification method for interactor B | Anti tag western blot |