| Unique identifier for interactor A | uniprotkb:O14787 |
| Unique identifier for interactor B | uniprotkb:P32835 |
| Alternative identifier for interactor A | intact:EBI-431907 uniprotkb:O14655 intact:EBI-1053477 uniprotkb:Q6IN77 ensembl:ENSP00000407182.1 ensembl:ENSP00000468434.1 |
| Alternative identifier for interactor B | intact:EBI-7926 uniprotkb:D6VYT9 |
| Aliases for A | psi-mi:tnpo2_human(display_long) uniprotkb:Karyopherin beta-2b(gene name synonym) uniprotkb:TNPO2(gene name) psi-mi:TNPO2(display_short) |
| Aliases for B | psi-mi:gsp1_yeast(display_long) uniprotkb:CNR1(gene name synonym) uniprotkb:CST17(gene name synonym) uniprotkb:GTPase Ran homolog(gene name synonym) uniprotkb:L8003.19(orf name) uniprotkb:YLR293C(locus name) uniprotkb:GSP1(gene name) psi-mi:GSP1(display_short) uniprotkb:Genetic suppressor of PRP20-1(gene name synonym) uniprotkb:Chromosome stability protein 17(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0096"(pull down) |
| First author | Volpon et al. (2016) |
| Identifier of the publication | pubmed:27114554 imex:IM-30416 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:559292(yeast) taxid:559292(Saccharomyces cerevisiae) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-67104179 imex:IM-30416-17 |
| Confidence score | intact-miscore:0.44 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:suppl.fig. 1a comment:"\"All of these bacterially produced and purified importins are active because they all bind a form of yeast Ran•GTP (guanosine triphosphate) [Glutathione S-transferase (GST)-GSP1] with mutations and deletions (GST-GSP1 1–179, Q71L) that stabilize the GTP-bound state (25) (Fig. S1A).\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2025/07/10 |
| Update date | 2025/08/13 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | mutation causing an interaction:71-71 binding-associated region:1-179 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Molecular weight estimation by coomasie staining |
| Participant identification method for interactor B | Molecular weight estimation by coomasie staining |