Curation Details
Interaction ID: IM-30416-13

Unique identifier for interactor Auniprotkb:P32835
Unique identifier for interactor Buniprotkb:Q96P70
Alternative identifier for interactor Aintact:EBI-7926
uniprotkb:D6VYT9
Alternative identifier for interactor Bintact:EBI-356319
intact:EBI-1059309
uniprotkb:Q8N1Y1
uniprotkb:Q8N3I2
uniprotkb:Q8NCG9
uniprotkb:Q96SU6
uniprotkb:Q9NW01
uniprotkb:Q9P0A8
uniprotkb:Q9ULM8
uniprotkb:B1ASV5
ensembl:ENSP00000354742.4
Aliases for Apsi-mi:gsp1_yeast(display_long)
uniprotkb:CNR1(gene name synonym)
uniprotkb:CST17(gene name synonym)
uniprotkb:GTPase Ran homolog(gene name synonym)
uniprotkb:L8003.19(orf name)
uniprotkb:YLR293C(locus name)
uniprotkb:GSP1(gene name)
psi-mi:GSP1(display_short)
uniprotkb:Genetic suppressor of PRP20-1(gene name synonym)
uniprotkb:Chromosome stability protein 17(gene name synonym)
Aliases for Bpsi-mi:ipo9_human(display_long)
uniprotkb:HSPC273(orf name)
uniprotkb:IPO9(gene name)
psi-mi:IPO9(display_short)
uniprotkb:IMP9(gene name synonym)
uniprotkb:KIAA1192(gene name synonym)
uniprotkb:RANBP9(gene name synonym)
uniprotkb:Ran-binding protein 9(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorVolpon et al. (2016)
Identifier of the publicationpubmed:27114554
imex:IM-30416
NCBI Taxonomy identifier for interactor Ataxid:559292(yeast)
taxid:559292(Saccharomyces cerevisiae)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-67104161
imex:IM-30416-13
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:suppl.fig. 1a
comment:"\"All of these bacterially produced and purified importins are active because they all bind a form of yeast Ran•GTP (guanosine triphosphate) [Glutathione S-transferase (GST)-GSP1] with mutations and deletions (GST-GSP1 1–179, Q71L) that stabilize the GTP-bound state (25) (Fig. S1A).\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2025/07/10
Update date2025/08/13
negative Boolean valuefalse
Feature(s) for interactor Amutation causing an interaction:71-71
binding-associated region:1-179
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AMolecular weight estimation by coomasie staining
Participant identification method for interactor BMolecular weight estimation by coomasie staining