Curation Details
Interaction ID: IM-30413-5

Unique identifier for interactor Achebi:"CHEBI:191209"
Unique identifier for interactor Buniprotkb:P06730
Alternative identifier for interactor Aintact:EBI-66895786
chebi:"CHEBI:157761"
Alternative identifier for interactor Bintact:EBI-73440
uniprotkb:Q96E95
uniprotkb:D6RCQ6
uniprotkb:B7Z6V1
ensembl:ENSP00000389624.2
intact:EBI-28969298
Aliases for Apsi-mi:7-methyl-guanosine-5'-triphosphate-5'-guanosine(display_short)
psi-mi:"CHEBI:191209"(display_long)
intact:7-methyl-diguanosine triphosphate(synonym)
intact:7-methyl-GpppG(synonym)
intact:"m(7)G(5')ppp(5')G"(synonym)
intact:"m(7)GP3G"(synonym)
intact:"[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-7-ium-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl] hydrogen phosphate"(synonym)
intact:"m(7)GP3G (monomethylated cap analog)"(synonym)
intact:"m(7)GpppG"(synonym)
intact:"mRNA cap analog N(7)-methyl GpppG"(synonym)
intact:"N(7)-MeGpppG"(synonym)
intact:"P(1)-(5'-7-methyl-guanosyl) P(3)-(5'-(guanosyl))triphosphate"(synonym)
intact:"2-amino-9-[(2R,3R,4S,5R)-5-({[{[{[{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxytetrahydrofuran-2-yl]-7-met"(iupac name)
Aliases for Bpsi-mi:if4e_human(display_long)
uniprotkb:mRNA cap-binding protein(gene name synonym)
uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)
uniprotkb:EIF4E(gene name)
psi-mi:EIF4E(display_short)
uniprotkb:EIF4EL1(gene name synonym)
uniprotkb:EIF4F(gene name synonym)
Interaction detection methodspsi-mi:"MI:0016"(circular dichroism)
First authorCohen et al. (2001)
Identifier of the publicationpubmed:11500381
imex:IM-30413
NCBI Taxonomy identifier for interactor Ataxid:-2(chemical synthesis)
taxid:-2("Chemical synthesis (Chemical synthesis)")
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-66895784
imex:IM-30413-5
Confidence scoreintact-miscore:0.56
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type ASmall molecule
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 6a
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2025/07/07
Update date2025/08/13
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant