Curation Details
Interaction ID: IM-30411-3

Unique identifier for interactor Auniprotkb:P06730
Unique identifier for interactor Buniprotkb:Q60953
Alternative identifier for interactor Aintact:EBI-73440
uniprotkb:Q96E95
uniprotkb:D6RCQ6
uniprotkb:B7Z6V1
ensembl:ENSP00000389624.2
intact:EBI-28969298
Alternative identifier for interactor Bintact:EBI-3895605
ensembl:ENSMUSP00000082816.5
uniprotkb:Q8CEJ1
uniprotkb:Q8VCC4
Aliases for Apsi-mi:if4e_human(display_long)
uniprotkb:mRNA cap-binding protein(gene name synonym)
uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)
uniprotkb:EIF4E(gene name)
psi-mi:EIF4E(display_short)
uniprotkb:EIF4EL1(gene name synonym)
uniprotkb:EIF4F(gene name synonym)
Aliases for Bpsi-mi:pml_mouse(display_long)
uniprotkb:Pml(gene name)
psi-mi:Pml(display_short)
Interaction detection methodspsi-mi:"MI:0663"(confocal microscopy)
First authorTopisirovic et al. (2002)
Identifier of the publicationpubmed:12167712
imex:IM-30411
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:10090(mouse)
taxid:10090(Mus musculus)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-66892723
imex:IM-30411-3
Confidence scoreintact-miscore:0.27
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig.10
comment:"\"Further, confocal microscopy data indicate that transfected eIF4E and endogenous PML colocalized before and after IFN treatment (Fig. 10) as observed for endogenous proteins (Figure 1).\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:10090(mouse-nih_3t3)
taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells)
Parameters of the interaction-
Creation date2025/07/03
Update date2025/08/13
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunostaining
Participant identification method for interactor BImmunostaining