| Unique identifier for interactor A | uniprotkb:P06730 |
| Unique identifier for interactor B | uniprotkb:O43148 |
| Alternative identifier for interactor A | intact:EBI-73440 uniprotkb:Q96E95 uniprotkb:D6RCQ6 uniprotkb:B7Z6V1 ensembl:ENSP00000389624.2 intact:EBI-28969298 |
| Alternative identifier for interactor B | intact:EBI-877832 uniprotkb:D3DUJ5 uniprotkb:O94996 uniprotkb:Q9UIJ9 uniprotkb:B0YJ90 ensembl:ENSP00000262173.3 ensembl:ENSP00000372804.2 ensembl:ENSP00000446426.1 ensembl:ENSP00000466252.1 |
| Aliases for A | psi-mi:if4e_human(display_long) uniprotkb:mRNA cap-binding protein(gene name synonym) uniprotkb:eIF-4F 25 kDa subunit(gene name synonym) uniprotkb:EIF4E(gene name) psi-mi:EIF4E(display_short) uniprotkb:EIF4EL1(gene name synonym) uniprotkb:EIF4F(gene name synonym) |
| Aliases for B | psi-mi:mces_human(display_long) uniprotkb:RG7MT1(gene name synonym) uniprotkb:mRNA cap methyltransferase(gene name synonym) uniprotkb:RNMT(gene name) psi-mi:RNMT(display_short) uniprotkb:KIAA0398(gene name synonym) uniprotkb:"mRNA (guanine-N(7))-methyltransferase"(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0077"(nuclear magnetic resonance) |
| First author | Osborne et al. (2022) |
| Identifier of the publication | pubmed:35026230 imex:IM-30410 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-66893365 imex:IM-30410-7 |
| Confidence score | intact-miscore:0.63 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:fig.1h; fig. 2b; suppl. fig.2b comment:"\"Competition experiments were carried out with GST-eIF4E pulldowns (Figure 2A) and 1H-15N HSQC NMR (Figure 2B) experiments in the presence of 20-fold excess of m7GDP. In both cases the presence of m7GDP cap did not diminish binding of RNMT to eIF4E.\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2025/07/02 |
| Update date | 2025/08/13 |
| negative Boolean value | false |
| Feature(s) for interactor A | mutation with no effect:159-159,157-157,162-162 |
| Feature(s) for interactor B | binding-associated region:164-416 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |