| Unique identifier for interactor A | uniprotkb:P06730 |
| Unique identifier for interactor B | uniprotkb:Q9BTL3 |
| Alternative identifier for interactor A | intact:EBI-73440 uniprotkb:Q96E95 uniprotkb:D6RCQ6 uniprotkb:B7Z6V1 ensembl:ENSP00000389624.2 intact:EBI-28969298 |
| Alternative identifier for interactor B | intact:EBI-744023 uniprotkb:Q2M1J8 ensembl:ENSP00000307181.3 |
| Aliases for A | psi-mi:if4e_human(display_long) uniprotkb:mRNA cap-binding protein(gene name synonym) uniprotkb:eIF-4F 25 kDa subunit(gene name synonym) uniprotkb:EIF4E(gene name) psi-mi:EIF4E(display_short) uniprotkb:EIF4EL1(gene name synonym) uniprotkb:EIF4F(gene name synonym) |
| Aliases for B | psi-mi:ramac_human(display_long) uniprotkb:RAMAC(gene name) psi-mi:RAMAC(display_short) uniprotkb:C15orf18(gene name synonym) uniprotkb:FAM103A1(gene name synonym) uniprotkb:Protein FAM103A1(gene name synonym) uniprotkb:RAMMET(gene name synonym) uniprotkb:RNA guanine-7 methyltransferase activating subunit(gene name synonym) uniprotkb:RNMT-activating mini protein(gene name synonym) uniprotkb:RNMT-activating mRNA cap methyltransferase subunit(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0096"(pull down) |
| First author | Osborne et al. (2022) |
| Identifier of the publication | pubmed:35026230 imex:IM-30410 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-66893387 imex:IM-30410-11 |
| Confidence score | intact-miscore:0.44 |
| Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
| Biological role A | Unspecified role |
| Biological role B | Competitor |
| Experimental role A | Bait |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:fig. 3b comment:"\"Competition experiments were carried out with GST-eIF4E pulldowns (Figure 2A) and 1H-15N HSQC NMR (Figure 2B) experiments in the presence of 20-fold excess of m7GDP. In both cases the presence of m7GDP cap did not diminish binding of RNMT to eIF4E.\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2025/07/02 |
| Update date | 2025/08/13 |
| negative Boolean value | false |
| Feature(s) for interactor A | glutathione s tranferase tag:?-? |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |