Curation Details
Interaction ID: IM-30387-1

Unique identifier for interactor Aintact:EBI-54294695
Unique identifier for interactor Bintact:EBI-25466420
Alternative identifier for interactor Aensembl:ENST00000316660
Alternative identifier for interactor Brefseq:NR_029639
mirbase:MIMAT0000318
rnacentral:URS000014D9C1_9606
Aliases for Apsi-mi:mrna_pmaip1(display_short)
psi-mi:EBI-54294695(display_long)
uniprotkb:PMAIP1(gene name)
Aliases for Bpsi-mi:hsa-mir-200b-3p(display_short)
psi-mi:EBI-25466420(display_long)
Interaction detection methodspsi-mi:"MI:2285"(miRNA interference luciferase reporter assay)
First authorShi et al. (2024)
Identifier of the publicationpubmed:38503887
imex:IM-30387
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-64059669
imex:IM-30387-1
Confidence scoreintact-miscore:0.28
Complex expansion-
Biological role ARegulator target
Biological role BRegulator
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AMessenger rna
Interactor type BMicro rna
Annotations for the interactionfigure legend:fig.3d-e
causality statement:down regulate quantity by destabilization
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2025/05/21
Update date2025/05/26
negative Boolean valuefalse
Feature(s) for interactor Amutation decreasing interaction:1454-1461
mutation decreasing interaction:1737-1744
luciferase tag:0-0
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ATag visualisation by luciferase assay
Participant identification method for interactor BPredetermined participant