Curation Details
Interaction ID: IM-30349-1

Unique identifier for interactor Aintact:EBI-54306870
Unique identifier for interactor Bintact:EBI-64039013
Alternative identifier for interactor Arnacentral:URS000050C722_9606
refseq:NR_030399
mirbase:MIMAT0003340
Alternative identifier for interactor Bensembl:ENST00000300177
Aliases for Apsi-mi:hsa-mir-542-5p(display_short)
psi-mi:EBI-54306870(display_long)
Aliases for Bpsi-mi:mrna_grem1(display_short)
psi-mi:EBI-64039013(display_long)
uniprotkb:GREM1(gene name)
Interaction detection methodspsi-mi:"MI:2285"(miRNA interference luciferase reporter assay)
First authorPang et al. (2024)
Identifier of the publicationpubmed:39180371
imex:IM-30349
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-64039010
imex:IM-30349-1
Confidence scoreintact-miscore:0.28
Complex expansion-
Biological role ARegulator
Biological role BRegulator target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AMicro rna
Interactor type BMessenger rna
Annotations for the interactionfigure legend:fig. 5
causality statement:down regulate quantity by destabilization
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hk2)
taxid:9606(Homo sapiens HK2 kidney proximal tubular cell)
Parameters of the interaction-
Creation date2025/04/24
Update date2025/06/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bmutation decreasing interaction:3620-3636
luciferase tag:0-0
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BTag visualisation by luciferase assay