Curation Details
Interaction ID: IM-30265-3

Unique identifier for interactor Aintact:EBI-61272873
Unique identifier for interactor Bintact:EBI-61272893
Alternative identifier for interactor Aensembl:ENST00000560346
Alternative identifier for interactor Brnacentral:URS0000116F83_9606
refseq:NR_036159
mirbase:MIMAT0015075
Aliases for Apsi-mi:mrna_pak6(display_short)
psi-mi:EBI-61272873(display_long)
uniprotkb:PAK6(gene name)
Aliases for Bpsi-mi:hsa-mir-3191-3p(display_short)
psi-mi:EBI-61272893(display_long)
Interaction detection methodspsi-mi:"MI:2285"(miRNA interference luciferase reporter assay)
First authorXie et al. (2024)
Identifier of the publicationpubmed:39696440
imex:IM-30265
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-61272910
imex:IM-30265-3
Confidence scoreintact-miscore:0.28
Complex expansion-
Biological role ARegulator target
Biological role BRegulator
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AMessenger rna
Interactor type BMicro rna
Annotations for the interactionfigure legend:fig.1a-b
causality statement:down regulate quantity by destabilization
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hep_3b)
taxid:9606(Homo sapiens Hep3B hepatocellular carcinoma cell)
Parameters of the interaction-
Creation date2025/02/10
Update date2025/02/24
negative Boolean valuefalse
Feature(s) for interactor Aluciferase tag:0-0
mutation decreasing interaction:3182-3188
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ATag visualisation by luciferase assay
Participant identification method for interactor BPredetermined participant