Curation Details
Interaction ID: IM-30264-1

Unique identifier for interactor Aintact:EBI-54267533
Unique identifier for interactor Bintact:EBI-54391372
Alternative identifier for interactor Arnacentral:URS00000F0F49_9606
refseq:NR_029946
mirbase:MIMAT0001341
Alternative identifier for interactor Bensembl:ENST00000361368
Aliases for Apsi-mi:hsa-mir-424-5p(display_short)
psi-mi:EBI-54267533(display_long)
Aliases for Bpsi-mi:mrna_smurf1(display_short)
psi-mi:EBI-54391372(display_long)
uniprotkb:SMURF1(gene name)
Interaction detection methodspsi-mi:"MI:2285"(miRNA interference luciferase reporter assay)
First authorWang et al. (2025)
Identifier of the publicationpubmed:39850720
imex:IM-30264
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-61269722
imex:IM-30264-1
Confidence scoreintact-miscore:0.54
Complex expansion-
Biological role ARegulator
Biological role BRegulator target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AMicro rna
Interactor type BMessenger rna
Annotations for the interactionfigure legend:fig. 3a
causality statement:down regulate quantity by destabilization
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293t)
taxid:9606(Homo sapiens HEK293T embryonic kidney cell)
Parameters of the interaction-
Creation date2025/02/10
Update date2025/03/06
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bluciferase tag:0-0
mutation decreasing interaction:5442-5448
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BTag visualisation by luciferase assay