Curation Details
Interaction ID: IM-30261-1

Unique identifier for interactor Aintact:EBI-36513712
Unique identifier for interactor Bintact:EBI-54331172
Alternative identifier for interactor Arnacentral:URS00001E3523_9606
Alternative identifier for interactor Bensembl:ENST00000245222
Aliases for Apsi-mi:hsa-mir-137-3p(display_short)
psi-mi:EBI-36513712(display_long)
Aliases for Bpsi-mi:mrna_sphk2(display_short)
psi-mi:EBI-54331172(display_long)
uniprotkb:SPHK2(gene name)
Interaction detection methodspsi-mi:"MI:2285"(miRNA interference luciferase reporter assay)
First authorLiu et al. (2023)
Identifier of the publicationpubmed:37533491
imex:IM-30261
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-61258324
imex:IM-30261-1
Confidence scoreintact-miscore:0.28
Complex expansion-
Biological role ARegulator
Biological role BRegulator target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AMicro rna
Interactor type BMessenger rna
Annotations for the interactionfigure legend:fig. 4 a-d
causality statement:down regulate quantity by destabilization
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-u373)
taxid:9606(Homo sapiens U373 glioblastoma astrocytoma cell)
Parameters of the interaction-
Creation date2025/02/03
Update date2025/08/13
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bluciferase tag:0-0
mutation decreasing interaction:2719-2724
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BTag visualisation by luciferase assay