Curation Details
Interaction ID: IM-30210-1

Unique identifier for interactor Aintact:EBI-54340657
Unique identifier for interactor Bintact:EBI-54401121
Alternative identifier for interactor Aensembl:ENST00000381652
Alternative identifier for interactor Brnacentral:URS0000450F92_9606
refseq:NR_030349
mirbase:MIMAT0003287
Aliases for Apsi-mi:mrna_jak2(display_short)
psi-mi:EBI-54340657(display_long)
uniprotkb:JAK2(gene name)
Aliases for Bpsi-mi:"(human) hsamir618"(display_short)
psi-mi:EBI-54401121(display_long)
Interaction detection methodspsi-mi:"MI:2285"(miRNA interference luciferase reporter assay)
First authorChen et al. (2024)
Identifier of the publicationpubmed:39716199
imex:IM-30210
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-61211085
imex:IM-30210-1
Confidence scoreintact-miscore:0.28
Complex expansion-
Biological role ARegulator target
Biological role BRegulator
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AMessenger rna
Interactor type BMicro rna
Annotations for the interactionfigure legend:fig. 3a-c
causality statement:down regulate quantity by destabilization
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-h1299)
taxid:9606(Homo sapiens H199 lung lymph node carcinoma cell)
Parameters of the interaction-
Creation date2025/01/08
Update date2025/08/13
negative Boolean valuefalse
Feature(s) for interactor Aluciferase tag:0-0
mutation decreasing interaction:6221-6226
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ATag visualisation by luciferase assay
Participant identification method for interactor BPredetermined participant