Curation Details
Interaction ID: IM-30148-9

Unique identifier for interactor Auniprotkb:Q06124
Unique identifier for interactor Buniprotkb:Q05397
Alternative identifier for interactor Aintact:EBI-297779
uniprotkb:Q96HD7
uniprotkb:A8K1D9
intact:EBI-14351608
intact:EBI-11988773
intact:EBI-13004965
ensembl:ENSP00000340944.3
Alternative identifier for interactor Bintact:EBI-702142
uniprotkb:Q14291
uniprotkb:Q9UD85
intact:EBI-11047590
uniprotkb:B4E2N6
uniprotkb:F5H4S4
ensembl:ENSP00000429474.1
ensembl:ENSP00000429911.1
uniprotkb:J3QT16
uniprotkb:Q8IYN9
Aliases for Apsi-mi:ptn11_human(display_long)
uniprotkb:PTPN11(gene name)
psi-mi:PTPN11(display_short)
uniprotkb:PTP2C(gene name synonym)
uniprotkb:SHPTP2(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)
uniprotkb:SH-PTP3(gene name synonym)
uniprotkb:SH-PTP2(gene name synonym)
Aliases for Bpsi-mi:fak1_human(display_long)
uniprotkb:PTK2(gene name)
psi-mi:PTK2(display_short)
uniprotkb:FAK(gene name synonym)
uniprotkb:FAK1(gene name synonym)
uniprotkb:pp125FAK(gene name synonym)
uniprotkb:Protein-tyrosine kinase 2(gene name synonym)
uniprotkb:Focal adhesion kinase-related nonkinase(gene name synonym)
uniprotkb:Protein phosphatase 1 regulatory subunit 71(gene name synonym)
uniprotkb:p125FAK(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorTsutsumi et al. (2006)
Identifier of the publicationpubmed:16354697
imex:IM-30148
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-55032878
imex:IM-30148-9
Confidence scoreintact-miscore:0.69
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 5c
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-ags)
taxid:9606(Homo sapiens AGS gastric adenocarcinoma cell)
Parameters of the interaction-
Creation date2024/06/18
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Amutation increasing interaction:459-459,425-425
myc tag:?-?
Feature(s) for interactor Bflag tag:?-?
mutation with no effect:861-861,407-407,925-925
mutation decreasing interaction:397-397
mutation decreasing interaction:576-577
mutation disrupting interaction:576-577,397-397
mutation disrupting interaction:576-577,397-397,407-407,861-861,925-925
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot