| Unique identifier for interactor A | uniprotkb:Q14790 |
| Unique identifier for interactor B | uniprotkb:O15111 |
| Alternative identifier for interactor A | intact:EBI-78060 uniprotkb:Q14793 uniprotkb:Q14794 uniprotkb:Q14795 uniprotkb:Q14796 uniprotkb:Q15780 uniprotkb:Q15806 uniprotkb:Q53TT5 uniprotkb:Q8TDI1 uniprotkb:Q8TDI2 uniprotkb:Q8TDI3 uniprotkb:Q8TDI4 uniprotkb:Q8TDI5 uniprotkb:Q96T22 uniprotkb:Q9C0K4 uniprotkb:O14676 uniprotkb:Q14791 uniprotkb:Q14792 uniprotkb:Q9UQ81 ensembl:ENSP00000396869.2 ensembl:ENSP00000397528.2 ensembl:ENSP00000412523.2 ensembl:ENSP00000501268.1 ensembl:ENSP00000512369.1 |
| Alternative identifier for interactor B | intact:EBI-81249 uniprotkb:O14666 uniprotkb:Q13132 uniprotkb:Q5W0I4 uniprotkb:Q92467 intact:EBI-28970970 ensembl:ENSP00000359424.6 |
| Aliases for A | psi-mi:casp8_human(display_long) uniprotkb:CASP8(gene name) psi-mi:CASP8(display_short) uniprotkb:MCH5(gene name synonym) uniprotkb:ICE-like apoptotic protease 5(gene name synonym) uniprotkb:MORT1-associated ced-3 homolog(gene name synonym) uniprotkb:FADD-homologous ICE/ced-3-like protease(gene name synonym) uniprotkb:FADD-like ICE(gene name synonym) uniprotkb:Apoptotic cysteine protease(gene name synonym) uniprotkb:Apoptotic protease Mch-5(gene name synonym) uniprotkb:CAP4(gene name synonym) |
| Aliases for B | psi-mi:ikka_human(display_long) uniprotkb:CHUK(gene name) psi-mi:CHUK(display_short) uniprotkb:IKKA(gene name synonym) uniprotkb:TCF16(gene name synonym) uniprotkb:I-kappa-B kinase 1(gene name synonym) uniprotkb:Conserved helix-loop-helix ubiquitous kinase(gene name synonym) uniprotkb:Nuclear factor NF-kappa-B inhibitor kinase alpha(gene name synonym) uniprotkb:Transcription factor 16(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
| First author | Contadini et al. (2023) |
| Identifier of the publication | pubmed:36460775 imex:IM-30081 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0914"(association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-55042563 imex:IM-30081-5 |
| Confidence score | intact-miscore:0.35 |
| Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F4C curation depth:imex curation dataset:Cancer - Interactions investigated in the context of cancer full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-u87-mg) taxid:9606(Homo sapiens U-87 MG glioblastoma cell) |
| Parameters of the interaction | - |
| Creation date | 2024/07/05 |
| Update date | 2025/08/05 |
| negative Boolean value | false |
| Feature(s) for interactor A | mutation disrupting interaction:380-380 |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |