Curation Details
Interaction ID: IM-30078-5

Unique identifier for interactor Auniprotkb:P12830
Unique identifier for interactor Bintact:EBI-55021380
Alternative identifier for interactor Aintact:EBI-727477
uniprotkb:Q13799
uniprotkb:Q14216
uniprotkb:Q15855
uniprotkb:Q16194
uniprotkb:Q4PJ14
uniprotkb:A8K1U7
ensembl:ENSP00000261769.4
intact:EBI-28986920
uniprotkb:Q9UII8
Alternative identifier for interactor B-
Aliases for Apsi-mi:cadh1_human(display_long)
uniprotkb:Uvomorulin(gene name synonym)
uniprotkb:Epithelial cadherin(gene name synonym)
uniprotkb:CAM 120/80(gene name synonym)
uniprotkb:CDH1(gene name)
psi-mi:CDH1(display_short)
uniprotkb:CDHE(gene name synonym)
uniprotkb:UVO(gene name synonym)
Aliases for Bpsi-mi:a0a2x5aby1_helpx(display_short)
psi-mi:EBI-55021380(display_long)
uniprotkb:cagA(gene name)
psi-mi:cagA(display_short)
uniprotkb:NCTC11637_00769(orf name)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorMurata-Kamiya et al. (2007)
Identifier of the publicationpubmed:17237808
imex:IM-30078
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)
taxid:102618(Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-55022078
imex:IM-30078-5
Confidence scoreintact-miscore:0.52
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 2c
comment:"\"Thus, CagA interacts with E-cadherin in a tyrosine phosphorylation-independent manner. Importantly, the CagA/E-cadherin complex failed to pull down β-catenin (Figure 2b, lane 2), whereas direct immunoprecipitation of the comparable amount of E-cadherin co-precipitated β-catenin (Figure 2b, lanes 3–5). The results indicated that the CagA/E-cadherin complex does not contain β-catenin.\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-mkn28)
taxid:9606(Homo sapiens MKN28 gastric tubular adenocarcinoma cell)
Parameters of the interaction-
Creation date2024/05/21
Update date2025/07/15
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bha tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot