| Unique identifier for interactor A | uniprotkb:Q8IV20 |
| Unique identifier for interactor B | uniprotkb:Q9NZJ5 |
| Alternative identifier for interactor A | intact:EBI-12508070 uniprotkb:A2A3Z6 uniprotkb:Q8N8X5 ensembl:ENSP00000317619.5 ensembl:ENSP00000391747.1 |
| Alternative identifier for interactor B | intact:EBI-766076 uniprotkb:A0AVH2 uniprotkb:A0AVH1 uniprotkb:B2RCU9 uniprotkb:Q53QY0 uniprotkb:Q53SB1 uniprotkb:O95846 ensembl:ENSP00000307235.3 |
| Aliases for A | psi-mi:lacc1_human(display_long) uniprotkb:LACC1(gene name) psi-mi:LACC1(display_short) uniprotkb:C13orf31(gene name synonym) uniprotkb:FAMIN(gene name synonym) uniprotkb:Fatty acid metabolism-immunity nexus(gene name synonym) uniprotkb:Adenosine deaminase LACC1(gene name synonym) uniprotkb:Guanosine phosphorylase LACC1(gene name synonym) uniprotkb:Laccase domain-containing protein 1(gene name synonym) uniprotkb:S-methyl-5'-thioadenosine phosphorylase LACC1(gene name synonym) |
| Aliases for B | psi-mi:e2ak3_human(display_long) uniprotkb:PRKR-like endoplasmic reticulum kinase(gene name synonym) uniprotkb:Pancreatic eIF2-alpha kinase(gene name synonym) uniprotkb:EIF2AK3(gene name) psi-mi:EIF2AK3(display_short) uniprotkb:PEK(gene name synonym) uniprotkb:PERK(gene name synonym) uniprotkb:Protein tyrosine kinase EIF2AK3(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
| First author | Huang et al. (2019) |
| Identifier of the publication | pubmed:31875558 imex:IM-30046 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0914"(association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-52361306 imex:IM-30046-3 |
| Confidence score | intact-miscore:0.35 |
| Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:fig.4e agonist:MDP Muramyl Dipeptide comment:"\"Consistent with this, LACC1-DISIK failed to associate with PERK, IRE1a, and ATF6 following NOD2 stimulation, but still maintained some association with RIP2 (Figure 4E), likely due to complex formation with cytoplasmic RIP2.\"" dataset:IBD - Inflammatory bowel disease curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-hela) taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell) |
| Parameters of the interaction | - |
| Creation date | 2024/03/05 |
| Update date | 2025/02/28 |
| negative Boolean value | false |
| Feature(s) for interactor A | necessary binding region:426-429 |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |