Curation Details
Interaction ID: IM-29871-1

Unique identifier for interactor Auniprotkb:P17612
Unique identifier for interactor Buniprotkb:P16220
Alternative identifier for interactor Aintact:EBI-476586
ensembl:ENSP00000309591.3
ensembl:ENSP00000499940.1
uniprotkb:Q32P54
uniprotkb:Q9H2Y0
uniprotkb:Q9NRB4
uniprotkb:Q9NRH9
Alternative identifier for interactor Bintact:EBI-711855
uniprotkb:Q6V963
ensembl:ENSP00000236995.3
ensembl:ENSP00000405539.1
uniprotkb:P21934
uniprotkb:Q9UMA7
intact:EBI-28970080
Aliases for Apsi-mi:kapca_human(display_long)
uniprotkb:PRKACA(gene name)
psi-mi:PRKACA(display_short)
uniprotkb:PKACA(gene name synonym)
Aliases for Bpsi-mi:creb1_human(display_long)
uniprotkb:CREB1(gene name)
psi-mi:CREB1(display_short)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorPan et al. (2022)
Identifier of the publicationimex:IM-29871
pubmed:37501933
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-46451554
imex:IM-29871-1
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 4d
comment:"\"Most importantly, endogenous PKA interacted with CREB, and this interaction was disrupted by VTN (Figure 4(d)).\""
antagonist:Vitronectin P04004
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-ht_29)
taxid:9606(Homo sapiens HT-29 colorectal adenocarcinoma cell)
Parameters of the interaction-
Creation date2023/09/18
Update date2023/09/18
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot