Curation Details
Interaction ID: IM-29863-7

Unique identifier for interactor Auniprotkb:Q9GZQ8
Unique identifier for interactor Buniprotkb:O43516
Alternative identifier for interactor Aintact:EBI-373144
ensembl:ENSP00000268607.5
ensembl:ENSP00000498476.1
intact:EBI-28979688
uniprotkb:Q6NW02
Alternative identifier for interactor Bintact:EBI-346356
uniprotkb:B8ZZM1
uniprotkb:D3DPE4
ensembl:ENSP00000352802.3
ensembl:ENSP00000376329.2
ensembl:ENSP00000376330.2
ensembl:ENSP00000388454.2
ensembl:ENSP00000503603.1
ensembl:ENSP00000513869.1
ensembl:ENSP00000513882.1
uniprotkb:Q15220
uniprotkb:Q6MZU9
uniprotkb:Q9BU37
uniprotkb:Q9UNP1
uniprotkb:Q53TA9
Aliases for Apsi-mi:mlp3b_human(display_long)
uniprotkb:MAP1LC3B(gene name)
psi-mi:MAP1LC3B(display_short)
uniprotkb:MAP1ALC3(gene name synonym)
uniprotkb:Microtubule-associated protein 1 light chain 3 beta(gene name synonym)
uniprotkb:MAP1A/MAP1B light chain 3 B(gene name synonym)
uniprotkb:MAP1 light chain 3-like protein 2(gene name synonym)
uniprotkb:Autophagy-related protein LC3 B(gene name synonym)
uniprotkb:Autophagy-related ubiquitin-like modifier LC3 B(gene name synonym)
Aliases for Bpsi-mi:wipf1_human(display_long)
uniprotkb:WIPF1(gene name)
psi-mi:WIPF1(display_short)
uniprotkb:WIP(gene name synonym)
uniprotkb:Wiskott-Aldrich syndrome protein-interacting protein(gene name synonym)
uniprotkb:Protein PRPL-2(gene name synonym)
uniprotkb:WASPIP(gene name synonym)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorDong et al. (2023)
Identifier of the publicationpubmed:36935496
imex:IM-29863
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-46450998
imex:IM-29863-7
Confidence scoreintact-miscore:0.46
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F3I SF4A
comment:"\"Moreover, we observed that WIP colocalized with LC3 in CLDN6-overexpressing breast cancer cells (Fig. 3I; Supplementary Fig. 4A, B). Thus, in the presence of CLDN6 overexpression, WIP may be recruited to autophagosome by LC3 to regulate autophagy.\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-mcf7)
taxid:9606(Homo sapiens MCF-7 mammary adenocarcinoma cell)
Parameters of the interaction-
Creation date2023/09/14
Update date2023/09/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunohistochemistry
Participant identification method for interactor BImmunohistochemistry