Curation Details
Interaction ID: IM-29863-11

Unique identifier for interactor Auniprotkb:P45983
Unique identifier for interactor Buniprotkb:P56747
Alternative identifier for interactor Aintact:EBI-286483
uniprotkb:B7ZLV4
uniprotkb:B5BTZ5
uniprotkb:Q308M2
uniprotkb:D3DX88
uniprotkb:D3DX92
ensembl:ENSP00000363304.1
uniprotkb:Q15709
uniprotkb:Q15712
uniprotkb:Q15713
Alternative identifier for interactor Bintact:EBI-12955011
uniprotkb:B3KQP9
uniprotkb:D3DUA5
ensembl:ENSP00000328674.4
ensembl:ENSP00000380131.1
Aliases for Apsi-mi:mk08_human(display_long)
uniprotkb:MAPK8(gene name)
psi-mi:MAPK8(display_short)
uniprotkb:JNK1(gene name synonym)
uniprotkb:PRKM8(gene name synonym)
uniprotkb:Stress-activated protein kinase JNK1(gene name synonym)
uniprotkb:c-Jun N-terminal kinase 1(gene name synonym)
uniprotkb:JNK-46(gene name synonym)
uniprotkb:SAPK1(gene name synonym)
uniprotkb:Stress-activated protein kinase 1c(gene name synonym)
uniprotkb:SAPK1C(gene name synonym)
Aliases for Bpsi-mi:cld6_human(display_long)
uniprotkb:CLDN6(gene name)
psi-mi:CLDN6(display_short)
uniprotkb:Skullin(gene name synonym)
uniprotkb:UNQ757/PRO1488(orf name)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorDong et al. (2023)
Identifier of the publicationpubmed:36935496
imex:IM-29863
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-46451010
imex:IM-29863-11
Confidence scoreintact-miscore:0.49
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F6C F6G
comment:"\"We created a mutant of CLDN6 (CLDN6ΔPBM) affecting its PBM. Moreover, the mutant CLDN6 was not able to interact with JNK (Fig. 6E-G).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-mda_mb_231)
taxid:9606(Homo sapiens MDA-MB-231 breast adenocarcinoma cell)
Parameters of the interaction-
Creation date2023/09/14
Update date2023/09/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot