Curation Details
Interaction ID: IM-29860-5

Unique identifier for interactor Auniprotkb:P46531
Unique identifier for interactor Buniprotkb:Q13153
Alternative identifier for interactor Aintact:EBI-636374
uniprotkb:Q59ED8
uniprotkb:Q5SXM3
intact:EBI-28989124
ensembl:ENSP00000498587.1
Alternative identifier for interactor Bintact:EBI-1307
uniprotkb:O75561
uniprotkb:Q13567
uniprotkb:Q32M53
uniprotkb:Q32M54
uniprotkb:Q86W79
ensembl:ENSP00000348696.4
intact:EBI-28976107
Aliases for Apsi-mi:notc1_human(display_long)
uniprotkb:Translocation-associated notch protein TAN-1(gene name synonym)
uniprotkb:NOTCH1(gene name)
psi-mi:NOTCH1(display_short)
uniprotkb:TAN1(gene name synonym)
Aliases for Bpsi-mi:pak1_human(display_long)
uniprotkb:PAK1(gene name)
psi-mi:PAK1(display_short)
uniprotkb:p21-activated kinase 1(gene name synonym)
uniprotkb:p65-PAK(gene name synonym)
uniprotkb:Alpha-PAK(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorFrick et al. (2020)
Identifier of the publicationimex:IM-29860
pubmed:33189893
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-46450339
imex:IM-29860-5
Confidence scoreintact-miscore:0.40
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f4d
antagonist:"\"Jagged1 (UniProt ID: P78504)\""
curation depth:imex curation
dataset:IBD - Inflammatory bowel disease
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hcec1ct)
taxid:9606(Homo sapiens HCEC1-CT colonic epithelial cell)
Parameters of the interaction-
Creation date2023/09/12
Update date2024/11/28
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot