| Unique identifier for interactor A | uniprotkb:P57739 |
| Unique identifier for interactor B | uniprotkb:Q96CW1 |
| Alternative identifier for interactor A | intact:EBI-751440 uniprotkb:B2R6B9 ensembl:ENSP00000336571.1 ensembl:ENSP00000441283.1 ensembl:ENSP00000443230.1 |
| Alternative identifier for interactor B | intact:EBI-297683 uniprotkb:A6NE12 uniprotkb:P20172 uniprotkb:P53679 uniprotkb:D3DNT1 ensembl:ENSP00000292807.5 |
| Aliases for A | psi-mi:cld2_human(display_long) uniprotkb:SP82(gene name synonym) uniprotkb:CLDN2(gene name) psi-mi:CLDN2(display_short) uniprotkb:PSEC0059(orf name) uniprotkb:SP82(orf name) uniprotkb:UNQ705/PRO1356(orf name) |
| Aliases for B | psi-mi:ap2m1_human(display_long) uniprotkb:Adaptor protein complex AP-2 subunit mu(gene name synonym) uniprotkb:AP-2 mu chain(gene name synonym) uniprotkb:AP2M1(gene name) psi-mi:AP2M1(display_short) uniprotkb:CLAPM1(gene name synonym) uniprotkb:KIAA0109(gene name synonym) uniprotkb:Adaptin-mu2(gene name synonym) uniprotkb:Plasma membrane adaptor AP-2 50 kDa protein(gene name synonym) uniprotkb:HA2 50 kDa subunit(gene name synonym) uniprotkb:Clathrin coat assembly protein AP50(gene name synonym) uniprotkb:Clathrin coat-associated protein AP50(gene name synonym) uniprotkb:Clathrin assembly protein complex 2 mu medium chain(gene name synonym) uniprotkb:Adaptor-related protein complex 2 subunit mu(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0416"(fluorescence microscopy) |
| First author | Ganapathy et al. (2022) |
| Identifier of the publication | pubmed:34964704 imex:IM-29857 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0403"(colocalization) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-46450246 imex:IM-29857-8 |
| Confidence score | intact-miscore:0.54 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F7C comment:"\"We also observed similar phenomenon upon confocal immunofluorescence examination where mutations in AP2M1 anchoring motifs in CLDN2 abrogated CLDN2-AP2M1 colocalization (Figure 7C).\"" curation depth:imex curation dataset:IBD - Inflammatory bowel disease full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-293) taxid:9606(Homo sapiens HEK293 embryonic kidney cell) |
| Parameters of the interaction | - |
| Creation date | 2023/09/12 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | green fluorescent protein tag:?-? mutation disrupting interaction:67-67,70-70,148-148,151-151 |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Immunocytochemistry |
| Participant identification method for interactor B | Immunocytochemistry |