Curation Details
Interaction ID: IM-29857-6

Unique identifier for interactor Auniprotkb:P57739
Unique identifier for interactor Buniprotkb:Q96CW1
Alternative identifier for interactor Aintact:EBI-751440
uniprotkb:B2R6B9
ensembl:ENSP00000336571.1
ensembl:ENSP00000441283.1
ensembl:ENSP00000443230.1
Alternative identifier for interactor Bintact:EBI-297683
uniprotkb:D3DNT1
ensembl:ENSP00000292807.5
uniprotkb:A6NE12
uniprotkb:P20172
uniprotkb:P53679
Aliases for Apsi-mi:cld2_human(display_long)
uniprotkb:SP82(gene name synonym)
uniprotkb:CLDN2(gene name)
psi-mi:CLDN2(display_short)
uniprotkb:PSEC0059(orf name)
uniprotkb:SP82(orf name)
uniprotkb:UNQ705/PRO1356(orf name)
Aliases for Bpsi-mi:ap2m1_human(display_long)
uniprotkb:Adaptor protein complex AP-2 subunit mu(gene name synonym)
uniprotkb:AP-2 mu chain(gene name synonym)
uniprotkb:AP2M1(gene name)
psi-mi:AP2M1(display_short)
uniprotkb:CLAPM1(gene name synonym)
uniprotkb:KIAA0109(gene name synonym)
uniprotkb:Adaptin-mu2(gene name synonym)
uniprotkb:Plasma membrane adaptor AP-2 50 kDa protein(gene name synonym)
uniprotkb:HA2 50 kDa subunit(gene name synonym)
uniprotkb:Clathrin coat assembly protein AP50(gene name synonym)
uniprotkb:Clathrin coat-associated protein AP50(gene name synonym)
uniprotkb:Clathrin assembly protein complex 2 mu medium chain(gene name synonym)
uniprotkb:Adaptor-related protein complex 2 subunit mu(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorGanapathy et al. (2022)
Identifier of the publicationpubmed:34964704
imex:IM-29857
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-46450221
imex:IM-29857-6
Confidence scoreintact-miscore:0.54
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F7B
dataset:IBD - Inflammatory bowel disease
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2023/09/12
Update date2023/09/12
negative Boolean valuefalse
Feature(s) for interactor Agreen fluorescent protein tag:?-?
mutation disrupting interaction strength:67-67,70-70
mutation decreasing interaction strength:148-148,151-151
mutation disrupting interaction strength:67-67,70-70,148-148,151-151
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot