| Unique identifier for interactor A | uniprotkb:P57739 |
| Unique identifier for interactor B | uniprotkb:Q9GZQ8 |
| Alternative identifier for interactor A | intact:EBI-751440 uniprotkb:B2R6B9 ensembl:ENSP00000336571.1 ensembl:ENSP00000441283.1 ensembl:ENSP00000443230.1 |
| Alternative identifier for interactor B | intact:EBI-373144 ensembl:ENSP00000268607.5 ensembl:ENSP00000498476.1 intact:EBI-28979688 uniprotkb:Q6NW02 |
| Aliases for A | psi-mi:cld2_human(display_long) uniprotkb:SP82(gene name synonym) uniprotkb:CLDN2(gene name) psi-mi:CLDN2(display_short) uniprotkb:PSEC0059(orf name) uniprotkb:SP82(orf name) uniprotkb:UNQ705/PRO1356(orf name) |
| Aliases for B | psi-mi:mlp3b_human(display_long) uniprotkb:MAP1LC3B(gene name) psi-mi:MAP1LC3B(display_short) uniprotkb:MAP1ALC3(gene name synonym) uniprotkb:Microtubule-associated protein 1 light chain 3 beta(gene name synonym) uniprotkb:MAP1A/MAP1B light chain 3 B(gene name synonym) uniprotkb:MAP1 light chain 3-like protein 2(gene name synonym) uniprotkb:Autophagy-related protein LC3 B(gene name synonym) uniprotkb:Autophagy-related ubiquitin-like modifier LC3 B(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0416"(fluorescence microscopy) |
| First author | Ganapathy et al. (2022) |
| Identifier of the publication | pubmed:34964704 imex:IM-29857 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0403"(colocalization) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-46450193 imex:IM-29857-5 |
| Confidence score | intact-miscore:0.43 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F6E comment:"\"Confocal immunofluorescence examination showed that, CLDN2 (green) migrated away from the cell membrane and increased cytoplasmic colocalization with clathrin (red) after starvation (yellow)...In confocal immunofluorescence examination, starvation induced increased colocalization of CLDN2 (green) and LC3 (red) when compared to control Caco-2 cells. AP2M1 KO cells showed prominent presence of CLDN2 (green) on the membrane with least colocalization with LC3 (red), even upon starvation.\"" dataset:IBD - Inflammatory bowel disease full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-caco2) taxid:9606(Homo sapiens CACO2 Caucasian colon adenocarcinoma cell) |
| Parameters of the interaction | - |
| Creation date | 2023/09/12 |
| Update date | 2023/09/12 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Immunohistochemistry |
| Participant identification method for interactor B | Immunohistochemistry |