Curation Details
Interaction ID: IM-29857-10

Unique identifier for interactor Auniprotkb:Q9GZQ8
Unique identifier for interactor Buniprotkb:Q96CW1
Alternative identifier for interactor Aintact:EBI-373144
uniprotkb:Q6NW02
ensembl:ENSP00000268607.5
ensembl:ENSP00000498476.1
intact:EBI-28979688
Alternative identifier for interactor Bintact:EBI-297683
uniprotkb:A6NE12
uniprotkb:P20172
uniprotkb:P53679
uniprotkb:D3DNT1
ensembl:ENSP00000292807.5
Aliases for Apsi-mi:mlp3b_human(display_long)
uniprotkb:MAP1LC3B(gene name)
psi-mi:MAP1LC3B(display_short)
uniprotkb:MAP1ALC3(gene name synonym)
uniprotkb:Microtubule-associated protein 1 light chain 3 beta(gene name synonym)
uniprotkb:MAP1A/MAP1B light chain 3 B(gene name synonym)
uniprotkb:MAP1 light chain 3-like protein 2(gene name synonym)
uniprotkb:Autophagy-related protein LC3 B(gene name synonym)
uniprotkb:Autophagy-related ubiquitin-like modifier LC3 B(gene name synonym)
Aliases for Bpsi-mi:ap2m1_human(display_long)
uniprotkb:Adaptor protein complex AP-2 subunit mu(gene name synonym)
uniprotkb:AP-2 mu chain(gene name synonym)
uniprotkb:AP2M1(gene name)
psi-mi:AP2M1(display_short)
uniprotkb:CLAPM1(gene name synonym)
uniprotkb:KIAA0109(gene name synonym)
uniprotkb:Adaptin-mu2(gene name synonym)
uniprotkb:Plasma membrane adaptor AP-2 50 kDa protein(gene name synonym)
uniprotkb:HA2 50 kDa subunit(gene name synonym)
uniprotkb:Clathrin coat assembly protein AP50(gene name synonym)
uniprotkb:Clathrin coat-associated protein AP50(gene name synonym)
uniprotkb:Clathrin assembly protein complex 2 mu medium chain(gene name synonym)
uniprotkb:Adaptor-related protein complex 2 subunit mu(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorGanapathy et al. (2022)
Identifier of the publicationpubmed:34964704
imex:IM-29857
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-46450274
imex:IM-29857-10
Confidence scoreintact-miscore:0.35
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F8C
comment:"\"The results showed an increase in the interaction of CLDN2 and AP2M1 with LC3 upon starvation in control cells (Figure 8C and D)\""
curation depth:imex curation
dataset:IBD - Inflammatory bowel disease
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-caco2)
taxid:9606(Homo sapiens CACO2 Caucasian colon adenocarcinoma cell)
Parameters of the interaction-
Creation date2023/09/12
Update date2024/11/28
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot