Curation Details
Interaction ID: IM-29855-3

Unique identifier for interactor Auniprotkb:P49327
Unique identifier for interactor Buniprotkb:Q16665
Alternative identifier for interactor Aintact:EBI-356658
uniprotkb:Q4LE83
uniprotkb:Q13479
uniprotkb:Q16702
uniprotkb:Q6P4U5
uniprotkb:Q6SS02
uniprotkb:Q969R1
uniprotkb:Q96C68
uniprotkb:Q96IT0
ensembl:ENSP00000304592.2
Alternative identifier for interactor Bintact:EBI-447269
uniprotkb:Q53XP6
uniprotkb:Q96PT9
uniprotkb:Q9UPB1
uniprotkb:C0LZJ3
ensembl:ENSP00000338018.4
Aliases for Apsi-mi:fas_human(display_long)
uniprotkb:FASN(gene name)
psi-mi:FASN(display_short)
uniprotkb:FAS(gene name synonym)
uniprotkb:Type I fatty acid synthase(gene name synonym)
Aliases for Bpsi-mi:hif1a_human(display_long)
uniprotkb:ARNT-interacting protein(gene name synonym)
uniprotkb:Member of PAS protein 1(gene name synonym)
uniprotkb:Basic-helix-loop-helix-PAS protein MOP1(gene name synonym)
uniprotkb:HIF1A(gene name)
psi-mi:HIF1A(display_short)
uniprotkb:MOP1(gene name synonym)
uniprotkb:BHLHE78(gene name synonym)
uniprotkb:PASD8(gene name synonym)
uniprotkb:PAS domain-containing protein 8(gene name synonym)
uniprotkb:Class E basic helix-loop-helix protein 78(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorLi et al. (2023)
Identifier of the publicationpubmed:36604718
imex:IM-29855
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-46449690
imex:IM-29855-3
Confidence scoreintact-miscore:0.46
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F5E
comment:"\"Further, IF and Co-IP analyses confirmed that FASN co-localizes with HIF1α in the cytoplasm under both normoxic and hypoxic conditions (Fig. 5D and E).\""
curation depth:imex curation
dataset:Cancer - Interactions investigated in the context of cancer
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-huh7)
taxid:9606(Homo sapiens Huh7 hepatoma cell)
Parameters of the interaction-
Creation date2023/09/11
Update date2023/09/11
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot