Unique identifier for interactor A | uniprotkb:P49327 |
Unique identifier for interactor B | uniprotkb:Q16665 |
Alternative identifier for interactor A | intact:EBI-356658 uniprotkb:Q4LE83 uniprotkb:Q13479 uniprotkb:Q16702 uniprotkb:Q6P4U5 uniprotkb:Q6SS02 uniprotkb:Q969R1 uniprotkb:Q96C68 uniprotkb:Q96IT0 ensembl:ENSP00000304592.2 |
Alternative identifier for interactor B | intact:EBI-447269 uniprotkb:Q53XP6 uniprotkb:Q96PT9 uniprotkb:Q9UPB1 uniprotkb:C0LZJ3 ensembl:ENSP00000338018.4 |
Aliases for A | psi-mi:fas_human(display_long) uniprotkb:FASN(gene name) psi-mi:FASN(display_short) uniprotkb:FAS(gene name synonym) uniprotkb:Type I fatty acid synthase(gene name synonym) |
Aliases for B | psi-mi:hif1a_human(display_long) uniprotkb:ARNT-interacting protein(gene name synonym) uniprotkb:Member of PAS protein 1(gene name synonym) uniprotkb:Basic-helix-loop-helix-PAS protein MOP1(gene name synonym) uniprotkb:HIF1A(gene name) psi-mi:HIF1A(display_short) uniprotkb:MOP1(gene name synonym) uniprotkb:BHLHE78(gene name synonym) uniprotkb:PASD8(gene name synonym) uniprotkb:PAS domain-containing protein 8(gene name synonym) uniprotkb:Class E basic helix-loop-helix protein 78(gene name synonym) |
Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
First author | Li et al. (2023) |
Identifier of the publication | pubmed:36604718 imex:IM-29855 |
NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
Interaction types | psi-mi:"MI:0915"(physical association) |
Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
Interaction identifier(s) in the corresponding source database | intact:EBI-46449690 imex:IM-29855-3 |
Confidence score | intact-miscore:0.46 |
Complex expansion | - |
Biological role A | Unspecified role |
Biological role B | Unspecified role |
Experimental role A | Bait |
Experimental role B | Prey |
Interactor type A | Protein |
Interactor type B | Protein |
Annotations for the interaction | figure legend:F5E comment:"\"Further, IF and Co-IP analyses confirmed that FASN co-localizes with HIF1α in the cytoplasm under both normoxic and hypoxic conditions (Fig. 5D and E).\"" curation depth:imex curation dataset:Cancer - Interactions investigated in the context of cancer full coverage:Only protein-protein interactions |
NCBI Taxonomy identifier for the host organism | taxid:9606(human-huh7) taxid:9606(Homo sapiens Huh7 hepatoma cell) |
Parameters of the interaction | - |
Creation date | 2023/09/11 |
Update date | 2023/09/11 |
negative Boolean value | false |
Feature(s) for interactor A | - |
Feature(s) for interactor B | - |
Stoichiometry for interactor A | - |
Stoichiometry for interactor B | - |
Participant identification method for interactor A | Western blot |
Participant identification method for interactor B | Western blot |