Curation Details
Interaction ID: IM-29847-3

Unique identifier for interactor Auniprotkb:P12931
Unique identifier for interactor Buniprotkb:P08581
Alternative identifier for interactor Aintact:EBI-621482
intact:EBI-1383910
uniprotkb:Q76P87
uniprotkb:E1P5V4
ensembl:ENSP00000362668.2
ensembl:ENSP00000362680.2
ensembl:ENSP00000508666.1
ensembl:ENSP00000509325.1
ensembl:ENSP00000517666.1
ensembl:ENSP00000517668.1
ensembl:ENSP00000517669.1
ensembl:ENSP00000517670.1
intact:EBI-28966850
uniprotkb:Q86VB9
uniprotkb:Q9H5A8
Alternative identifier for interactor Bintact:EBI-1039152
uniprotkb:A1L467
uniprotkb:B5A932
uniprotkb:E7EQ94
ensembl:ENSP00000380860.3
uniprotkb:O60366
uniprotkb:Q12875
uniprotkb:Q9UDX7
uniprotkb:Q9UPL8
Aliases for Apsi-mi:src_human(display_long)
uniprotkb:pp60c-src(gene name synonym)
uniprotkb:SRC(gene name)
psi-mi:SRC(display_short)
uniprotkb:SRC1(gene name synonym)
uniprotkb:Proto-oncogene c-Src(gene name synonym)
Aliases for Bpsi-mi:met_human(display_long)
uniprotkb:MET(gene name)
psi-mi:MET(display_short)
uniprotkb:Scatter factor receptor(gene name synonym)
uniprotkb:HGF/SF receptor(gene name synonym)
uniprotkb:Tyrosine-protein kinase Met(gene name synonym)
uniprotkb:Proto-oncogene c-Met(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorAcevedo et al. (2022)
Identifier of the publicationpubmed:35405500
imex:IM-29847
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-46418021
imex:IM-29847-3
Confidence scoreintact-miscore:0.79
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:"\"We then assessed for potential interactions among CCR2, MET and SRC in CCL2-treated cells. CCL2 treatment of DCIS.com cells resulted in coimmunoprecipitation of MET with CCR2 and SRC, and SRC with MET and CCR2 (Fig. 1F).\""
figure legend:Fig.1f
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-mcf10a)
taxid:9606(Homo sapiens MCF10a non-transformed breast epithelial cell)
Parameters of the interaction-
Creation date2023/07/03
Update date2023/07/19
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot