Curation Details
Interaction ID: IM-29822-5

Unique identifier for interactor Auniprotkb:P61073
Unique identifier for interactor Buniprotkb:Q13304-2
Alternative identifier for interactor Aintact:EBI-489411
ensembl:ENSP00000241393.3
uniprotkb:Q53S69
uniprotkb:O60835
uniprotkb:P30991
uniprotkb:P56438
uniprotkb:Q9UKN2
uniprotkb:B2R5N0
uniprotkb:Q9BXA0
Alternative identifier for interactor Bintact:EBI-45351003
ensembl:ENSP00000508383.1
Aliases for Apsi-mi:cxcr4_human(display_long)
uniprotkb:Stromal cell-derived factor 1 receptor(gene name synonym)
uniprotkb:Fusin(gene name synonym)
uniprotkb:Leukocyte-derived seven transmembrane domain receptor(gene name synonym)
uniprotkb:LCR1(gene name synonym)
uniprotkb:FB22(gene name synonym)
uniprotkb:NPYRL(gene name synonym)
uniprotkb:HM89(gene name synonym)
uniprotkb:CXCR4(gene name)
psi-mi:CXCR4(display_short)
uniprotkb:Lipopolysaccharide-associated protein 3(gene name synonym)
Aliases for Bpsi-mi:q13304-2(display_long)
uniprotkb:GPR17(gene name)
psi-mi:GPR17(display_short)
uniprotkb:G-protein coupled receptor 17(gene name synonym)
uniprotkb:P2Y-like receptor(gene name synonym)
uniprotkb:R12(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorDaniele et al. (2022)
Identifier of the publicationimex:IM-29822
pubmed:36613703
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-45379273
imex:IM-29822-5
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 3
antagonist:"\"Cangrelor (GPR17 receptor antagonist, 1 nM)\""
antagonist:"\"Asinex 1 (GPR17 receptor agonist, 5 nM)\""
antagonist:"\"SB225002 (CXCR2 receptor antagonist, 1 μM)\""
agonist:"\"IL-8 (CXCR2 receptor agonist, 10 nM)\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-astrocytoma)
taxid:9606(Homo sapiens astrocytoma)
Parameters of the interaction-
Creation date2023/07/03
Update date2023/07/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bha tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot