Curation Details
Interaction ID: IM-29821-9

Unique identifier for interactor Auniprotkb:Q9NZ52
Unique identifier for interactor Buniprotkb:Q13258
Alternative identifier for interactor Aintact:EBI-447404
ensembl:ENSP00000438085.3
ensembl:ENSP00000496890.1
uniprotkb:B7Z7E2
uniprotkb:B7Z7M9
uniprotkb:J3KRN0
intact:EBI-28988067
uniprotkb:Q15017
uniprotkb:Q6IS16
uniprotkb:Q9UJY3
Alternative identifier for interactor Bintact:EBI-20731195
ensembl:ENSP00000303424.2
uniprotkb:G3V5L3
uniprotkb:Q13250
uniprotkb:Q13251
uniprotkb:Q1ZZ52
Aliases for Apsi-mi:gga3_human(display_long)
uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 3(gene name synonym)
uniprotkb:GGA3(gene name)
psi-mi:GGA3(display_short)
uniprotkb:KIAA0154(gene name synonym)
Aliases for Bpsi-mi:pd2r_human(display_long)
uniprotkb:Prostanoid DP receptor(gene name synonym)
uniprotkb:PTGDR(gene name)
psi-mi:PTGDR(display_short)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorFréchette et al. (2020)
Identifier of the publicationpubmed:32334026
imex:IM-29821
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-44447332
imex:IM-29821-9
Confidence scoreintact-miscore:0.61
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 3
agonist:"\"prostaglandin D2 CHEBI:15555\""
comment:"\"Confocal microscopy was then performed to determine whether DP1 and GGA3 colocalize intracellularly in the basal state and after DP1 activation with PGD2 for 15 min in HEK293 cells (Fig. 3). There was virtually no colocalization between Flag-DP1 and Myc-GGA3 in absence of agonist stimulation (Fig. 3 upper panel). On the other hand, colocalization of the two proteins was noticeably enhanced by PGD2 stimulation (Fig. 3, lower panel) as shown by the increase in colocalizing pixels.\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2023/05/25
Update date2023/06/14
negative Boolean valuefalse
Feature(s) for interactor Amyc tag:?-?
Feature(s) for interactor Bflag tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunostaining
Participant identification method for interactor BImmunostaining