| Unique identifier for interactor A | uniprotkb:P42336 |
| Unique identifier for interactor B | uniprotkb:P21860 |
| Alternative identifier for interactor A | intact:EBI-2116585 uniprotkb:Q14CW1 uniprotkb:Q99762 ensembl:ENSP00000263967.3 |
| Alternative identifier for interactor B | intact:EBI-720706 uniprotkb:A8K6L6 uniprotkb:B4DIK7 uniprotkb:B4DV32 uniprotkb:E9PDT8 uniprotkb:Q9BUD7 ensembl:ENSP00000267101.4 |
| Aliases for A | psi-mi:pk3ca_human(display_long) uniprotkb:Phosphoinositide-3-kinase catalytic alpha polypeptide(gene name synonym) uniprotkb:Serine/threonine protein kinase PIK3CA(gene name synonym) uniprotkb:PIK3CA(gene name) psi-mi:PIK3CA(display_short) uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha(gene name synonym) uniprotkb:Phosphoinositide 3-kinase alpha(gene name synonym) |
| Aliases for B | psi-mi:erbb3_human(display_long) uniprotkb:Tyrosine kinase-type cell surface receptor HER3(gene name synonym) uniprotkb:ERBB3(gene name) psi-mi:ERBB3(display_short) uniprotkb:HER3(gene name synonym) uniprotkb:Proto-oncogene-like protein c-ErbB-3(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Swaney et al. (2021) |
| Identifier of the publication | pubmed:34591642 imex:IM-29816 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-44458597 imex:IM-29816-232 |
| Confidence score | intact-miscore:0.72 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:SF6D curation depth:imex curation dataset:Cancer - Interactions investigated in the context of cancer full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-cal27) taxid:9606(Homo sapiens CAL-27 oral squamous carcinoma cell) |
| Parameters of the interaction | - |
| Creation date | 2022/07/06 |
| Update date | 2025/07/09 |
| negative Boolean value | false |
| Feature(s) for interactor A | flag tag:n-n mutation increasing interaction:542-542(rs121913273) mutation with no effect:1047-1047(rs121913279) mutation increasing interaction:545-545(rs104886003) |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |