Curation Details
Interaction ID: IM-29816-177

Unique identifier for interactor Auniprotkb:P42336
Unique identifier for interactor Buniprotkb:O00459
Alternative identifier for interactor Aintact:EBI-2116585
uniprotkb:Q14CW1
uniprotkb:Q99762
ensembl:ENSP00000263967.3
Alternative identifier for interactor Bintact:EBI-346930
uniprotkb:Q5EAT5
uniprotkb:Q9UPH9
intact:EBI-28974273
ensembl:ENSP00000222254.6
Aliases for Apsi-mi:pk3ca_human(display_long)
uniprotkb:Phosphoinositide-3-kinase catalytic alpha polypeptide(gene name synonym)
uniprotkb:Serine/threonine protein kinase PIK3CA(gene name synonym)
uniprotkb:PIK3CA(gene name)
psi-mi:PIK3CA(display_short)
uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha(gene name synonym)
uniprotkb:Phosphoinositide 3-kinase alpha(gene name synonym)
Aliases for Bpsi-mi:p85b_human(display_long)
uniprotkb:PIK3R2(gene name)
psi-mi:PIK3R2(display_short)
uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorSwaney et al. (2021)
Identifier of the publicationpubmed:34591642
imex:IM-29816
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-34585309
imex:IM-29816-177
Confidence scoreintact-miscore:0.90
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST2 ST3
curation depth:imex curation
dataset:Cancer - Interactions investigated in the context of cancer
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-Het1A)
taxid:9606(Homo sapiens Het1A oesophageal squamous cell)
Parameters of the interaction-
Creation date2022/07/06
Update date2024/07/30
negative Boolean valuefalse
Feature(s) for interactor Aflag tag:n-n
mutation:453-453
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AIdentification by mass spectrometry
Participant identification method for interactor BIdentification by mass spectrometry