Curation Details
Interaction ID: IM-29788-3

Unique identifier for interactor Auniprotkb:P08581
Unique identifier for interactor Buniprotkb:Q8TCU6
Alternative identifier for interactor Aintact:EBI-1039152
uniprotkb:O60366
uniprotkb:Q12875
uniprotkb:Q9UDX7
uniprotkb:Q9UPL8
uniprotkb:A1L467
uniprotkb:B5A932
uniprotkb:E7EQ94
ensembl:ENSP00000380860.3
Alternative identifier for interactor Bintact:EBI-1046542
uniprotkb:E1P5X9
uniprotkb:Q5JS95
uniprotkb:Q5JS96
uniprotkb:Q69YL2
uniprotkb:Q7Z2L9
uniprotkb:Q9BQH0
uniprotkb:Q9BX55
uniprotkb:Q9H4Q6
uniprotkb:Q9P2D2
uniprotkb:Q9UGQ4
ensembl:ENSP00000361009.3
Aliases for Apsi-mi:met_human(display_long)
uniprotkb:MET(gene name)
psi-mi:MET(display_short)
uniprotkb:Scatter factor receptor(gene name synonym)
uniprotkb:HGF/SF receptor(gene name synonym)
uniprotkb:Tyrosine-protein kinase Met(gene name synonym)
uniprotkb:Proto-oncogene c-Met(gene name synonym)
Aliases for Bpsi-mi:prex1_human(display_long)
uniprotkb:PREX1(gene name)
psi-mi:PREX1(display_short)
uniprotkb:KIAA1415(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorQiu et al. (2019)
Identifier of the publicationpubmed:33061433
imex:IM-29788
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-44438230
imex:IM-29788-3
Confidence scoreintact-miscore:0.52
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 7b
comment:"\"More importantly, a markedly improved interaction between endogenous P-Rex1 and c-Met was observed after HGF treatment for 30 min (P < 0.001, Figure 7B-D)\""
agonist:HGF P14210
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-sk-hep-1)
taxid:9606(Homo sapiens SK-HEP-1 liver adenocarcinoma cell)
Parameters of the interaction-
Creation date2023/05/25
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot