Curation Details
Interaction ID: IM-29725-39

Unique identifier for interactor Auniprotkb:Q9Y6A5
Unique identifier for interactor Buniprotkb:P00533
Alternative identifier for interactor Aintact:EBI-2554984
uniprotkb:Q9UMQ1
uniprotkb:Q3KQS5
uniprotkb:Q2NKK4
ensembl:ENSP00000326550.4
ensembl:ENSP00000498361.1
Alternative identifier for interactor Bintact:EBI-297353
uniprotkb:Q9BZS2
uniprotkb:Q9GZX1
uniprotkb:Q9H2C9
uniprotkb:Q9H3C9
uniprotkb:Q9UMD7
uniprotkb:Q9UMD8
uniprotkb:Q9UMG5
uniprotkb:O00688
uniprotkb:O00732
uniprotkb:P06268
uniprotkb:Q14225
uniprotkb:Q92795
intact:EBI-28985169
uniprotkb:Q68GS5
ensembl:ENSP00000275493.2
Aliases for Apsi-mi:tacc3_human(display_long)
uniprotkb:ERIC1(gene name synonym)
uniprotkb:ERIC-1(gene name synonym)
uniprotkb:TACC3(gene name)
psi-mi:TACC3(display_short)
Aliases for Bpsi-mi:egfr_human(display_long)
uniprotkb:ERBB1(gene name synonym)
uniprotkb:EGFR(gene name)
psi-mi:EGFR(display_short)
uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)
uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)
uniprotkb:ERBB(gene name synonym)
uniprotkb:HER1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorPetschnigg et al. (2017)
Identifier of the publicationpubmed:27956147
imex:IM-29725
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-42469308
imex:IM-29725-39
Confidence scoreintact-miscore:0.51
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:Fig. 3C
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293f)
taxid:9606(Homo sapiens HEK293F embryonic kidney cell)
Parameters of the interaction-
Creation date2018/10/16
Update date2024/07/10
negative Boolean valuefalse
Feature(s) for interactor Aflag tag:?-?
Feature(s) for interactor Bgreen fluorescent protein tag:c-c
mutation increasing interaction strength:746-750
mutation increasing interaction strength:858-858
mutation increasing interaction strength:858-858,790-790
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot