Curation Details
Interaction ID: IM-29722-3

Unique identifier for interactor Auniprotkb:P17918
Unique identifier for interactor Buniprotkb:Q62318
Alternative identifier for interactor Aintact:EBI-1173716
ensembl:ENSMUSP00000028817.7
Alternative identifier for interactor Bintact:EBI-346909
uniprotkb:P70391
uniprotkb:Q8C283
uniprotkb:Q99PN4
ensembl:ENSMUSP00000005705.8
Aliases for Apsi-mi:pcna_mouse(display_long)
uniprotkb:Pcna(gene name)
psi-mi:Pcna(display_short)
uniprotkb:Cyclin(gene name synonym)
Aliases for Bpsi-mi:tif1b_mouse(display_long)
uniprotkb:Trim28(gene name)
psi-mi:Trim28(display_short)
uniprotkb:Krip1(gene name synonym)
uniprotkb:Tif1b(gene name synonym)
uniprotkb:Tripartite motif-containing protein 28(gene name synonym)
uniprotkb:KRAB-A-interacting protein(gene name synonym)
uniprotkb:KRIP-1(gene name synonym)
uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)
uniprotkb:Kap1(gene name synonym)
uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorWang et al. (2022)
Identifier of the publicationpubmed:35799276
imex:IM-29722
NCBI Taxonomy identifier for interactor Ataxid:10090(mouse)
taxid:10090(Mus musculus)
NCBI Taxonomy identifier for interactor Btaxid:10090(mouse)
taxid:10090(Mus musculus)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-40252501
imex:IM-29722-3
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 5d
comment:"\"We also confrmed the interaction of KAP1 with PCNA in C17.2 cells by immunoprecipitation and found that this interaction decreased after OGD/R (Fig. 5D, E). For this condition, we found that simulated p-KAP1 could increase its association with PCNA (Fig. 5F).\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:10090("mouse-neuronal_precursor_cells(stem cells)")
taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells)
Parameters of the interaction-
Creation date2022/11/28
Update date2023/02/22
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot