Curation Details
Interaction ID: IM-29713-9

Unique identifier for interactor Auniprotkb:Q29ST3
Unique identifier for interactor Buniprotkb:P62820
Alternative identifier for interactor Aintact:EBI-15838677
Alternative identifier for interactor Bintact:EBI-716845
uniprotkb:Q96N61
uniprotkb:Q9Y3T2
uniprotkb:P11476
uniprotkb:Q6FIE7
ensembl:ENSP00000387286.3
ensembl:ENSP00000497078.1
Aliases for Apsi-mi:drra_legpn(display_long)
uniprotkb:drrA(gene name)
psi-mi:drrA(display_short)
uniprotkb:sidM(gene name synonym)
uniprotkb:Defects in Rab1 recruitment protein A(gene name synonym)
Aliases for Bpsi-mi:rab1a_human(display_long)
uniprotkb:YPT1-related protein(gene name synonym)
uniprotkb:RAB1A(gene name)
psi-mi:RAB1A(display_short)
uniprotkb:RAB1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0415"(enzymatic study)
First authorWang et al. (2017)
Identifier of the publicationpubmed:30323948
imex:IM-29713
NCBI Taxonomy identifier for interactor Ataxid:446(legpn)
taxid:446(Legionella pneumophila)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:1148"(ampylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-40255327
imex:IM-29713-9
Confidence scoreintact-miscore:0.54
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 5a
comment:"\"Of note is that despite the proximity of the major glucosylation site on Rab1 to residues attacked by L. pneumophila effectors SidM and AnkX, modification of Thr75 by SetA does not detectably interfere with subsequent AMPylation of Tyr80 or phosphorylcholinationof Ser79 (Fig. 5a, b).\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2023/01/31
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Ahis tag:?-?
Feature(s) for interactor Bglutathione s tranferase tag:?-?
modified L-tyrosine residue:75-75
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ASequence tag identification
Participant identification method for interactor BSequence tag identification