Curation Details
Interaction ID: IM-29713-23

Unique identifier for interactor Auniprotkb:Q5ZU30
Unique identifier for interactor Buniprotkb:P62820
Alternative identifier for interactor Aintact:EBI-40253342
Alternative identifier for interactor Bintact:EBI-716845
uniprotkb:Q6FIE7
ensembl:ENSP00000387286.3
ensembl:ENSP00000497078.1
uniprotkb:Q96N61
uniprotkb:Q9Y3T2
uniprotkb:P11476
Aliases for Apsi-mi:seta_legph(display_long)
uniprotkb:Effector protein SetA(gene name synonym)
uniprotkb:Subversion of eukaryotic vesicle trafficking A(gene name synonym)
uniprotkb:lpg1978(locus name)
uniprotkb:setA(gene name)
psi-mi:setA(display_short)
Aliases for Bpsi-mi:rab1a_human(display_long)
uniprotkb:YPT1-related protein(gene name synonym)
uniprotkb:RAB1A(gene name)
psi-mi:RAB1A(display_short)
uniprotkb:RAB1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0415"(enzymatic study)
First authorWang et al. (2017)
Identifier of the publicationpubmed:30323948
imex:IM-29713
NCBI Taxonomy identifier for interactor Ataxid:272624(legph)
taxid:272624(Legionella pneumophila subsp. pneumophila)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0559"(glycosylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-40255428
imex:IM-29713-23
Confidence scoreintact-miscore:0.52
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:suppl fig 10
comment:"\"Furthermore, we evaluated the in vitro modification ratios by loading purified Rab1 with either GDP or a nonhydrolyzable GTP analog GTPγS. Upon incubation with SetA, LC-MS analyses revealed a higher modification ratio (2–3 fold) of Rab1:GDP than that of Rab1:GTP (Fig. 4b).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:562(ecolx)
taxid:562(Escherichia coli)
Parameters of the interaction-
Creation date2023/01/31
Update date2023/02/27
negative Boolean valuefalse
Feature(s) for interactor Amutation disrupting interaction:134-134,136-136
his tag:?-?
Feature(s) for interactor Bglutathione s tranferase tag:?-?
glycosylated residue:75-75
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ASequence tag identification
Participant identification method for interactor BSequence tag identification