Curation Details
Interaction ID: IM-29713-17

Unique identifier for interactor Auniprotkb:Q5ZU30
Unique identifier for interactor Buniprotkb:P51149
Alternative identifier for interactor Aintact:EBI-40253342
Alternative identifier for interactor Bintact:EBI-1056089
ensembl:ENSP00000265062.3
ensembl:ENSP00000501618.1
ensembl:ENSP00000502000.1
ensembl:ENSP00000502088.1
ensembl:ENSP00000502486.1
uniprotkb:A8K3V6
uniprotkb:Q9NWJ0
uniprotkb:Q9UPB0
Aliases for Apsi-mi:seta_legph(display_long)
uniprotkb:Effector protein SetA(gene name synonym)
uniprotkb:Subversion of eukaryotic vesicle trafficking A(gene name synonym)
uniprotkb:lpg1978(locus name)
uniprotkb:setA(gene name)
psi-mi:setA(display_short)
Aliases for Bpsi-mi:rab7a_human(display_long)
uniprotkb:RAB7A(gene name)
psi-mi:RAB7A(display_short)
uniprotkb:RAB7(gene name synonym)
Interaction detection methodspsi-mi:"MI:0415"(enzymatic study)
First authorWang et al. (2017)
Identifier of the publicationpubmed:30323948
imex:IM-29713
NCBI Taxonomy identifier for interactor Ataxid:272624(legph)
taxid:272624(Legionella pneumophila subsp. pneumophila)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0559"(glycosylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-40255392
imex:IM-29713-17
Confidence scoreintact-miscore:0.52
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:suppl fig 5a
comment:"\"Furthermore, we evaluated the in vitro modification ratios by loading purified Rab1 with either GDP or a nonhydrolyzable GTP analog GTPγS. Upon incubation with SetA, LC-MS analyses revealed a higher modification ratio (2–3 fold) of Rab1:GDP than that of Rab1:GTP (Fig. 4b).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2023/01/31
Update date2023/02/27
negative Boolean valuefalse
Feature(s) for interactor Amutation disrupting interaction:134-134,136-136
his tag:?-?
Feature(s) for interactor Bglutathione s tranferase tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ASequence tag identification
Participant identification method for interactor BSequence tag identification