Curation Details
Interaction ID: IM-29713-11

Unique identifier for interactor Auniprotkb:Q5ZXN6
Unique identifier for interactor Buniprotkb:P62820
Alternative identifier for interactor Aintact:EBI-26359852
Alternative identifier for interactor Bintact:EBI-716845
uniprotkb:Q6FIE7
ensembl:ENSP00000387286.3
ensembl:ENSP00000497078.1
uniprotkb:Q96N61
uniprotkb:Q9Y3T2
uniprotkb:P11476
Aliases for Apsi-mi:ankx_legph(display_long)
uniprotkb:ankX(gene name)
psi-mi:ankX(display_short)
uniprotkb:legA8(gene name synonym)
uniprotkb:lpg0695(locus name)
uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)
Aliases for Bpsi-mi:rab1a_human(display_long)
uniprotkb:YPT1-related protein(gene name synonym)
uniprotkb:RAB1A(gene name)
psi-mi:RAB1A(display_short)
uniprotkb:RAB1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0415"(enzymatic study)
First authorWang et al. (2017)
Identifier of the publicationpubmed:30323948
imex:IM-29713
NCBI Taxonomy identifier for interactor Ataxid:272624(legph)
taxid:272624(Legionella pneumophila subsp. pneumophila)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0414"(enzymatic reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-40255341
imex:IM-29713-11
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 5b
comment:"\"Of note is that despite the proximity of the major glucosylation site on Rab1 to residues attacked by L. pneumophila effectors SidM and AnkX, modification of Thr75 by SetA does not detectably interfere with subsequent AMPylation of Tyr80 or phosphorylcholinationof Ser79 (Fig. 5a, b).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2023/01/31
Update date2023/02/27
negative Boolean valuefalse
Feature(s) for interactor Ahis tag:?-?
Feature(s) for interactor Bglutathione s tranferase tag:?-?
modified L-tyrosine residue:79-79
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ASequence tag identification
Participant identification method for interactor BSequence tag identification