Curation Details
Interaction ID: IM-29710-3

Unique identifier for interactor Auniprotkb:A0A3B6UEL2
Unique identifier for interactor Buniprotkb:P01116
Alternative identifier for interactor Aintact:EBI-40255461
Alternative identifier for interactor Bintact:EBI-367415
uniprotkb:A8K8Z5
ensembl:ENSP00000256078.5
uniprotkb:P01118
uniprotkb:Q96D10
uniprotkb:B0LPF9
Aliases for Apsi-mi:a0a3b6uel2_vibvl(display_long)
uniprotkb:XM78_c20952(orf name)
Aliases for Bpsi-mi:rask_human(display_long)
uniprotkb:KRAS(gene name)
psi-mi:KRAS(display_short)
uniprotkb:RASK2(gene name synonym)
uniprotkb:KRAS2(gene name synonym)
uniprotkb:K-Ras 2(gene name synonym)
uniprotkb:Ki-Ras(gene name synonym)
uniprotkb:c-K-ras(gene name synonym)
uniprotkb:c-Ki-ras(gene name synonym)
Interaction detection methodspsi-mi:"MI:0415"(enzymatic study)
First authorBiancucci et al. (2018)
Identifier of the publicationpubmed:30279169
imex:IM-29710
NCBI Taxonomy identifier for interactor Ataxid:672(vibvl)
taxid:672(Vibrio vulnificus)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0194"(cleavage reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-40255481
imex:IM-29710-3
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 3, 4
comment:"\"Chelator-treated rRRSP did not show inhibition of activity, even at the highest molar ratio of 1:500 (RRSP:chelator) (Fig. 4,A and B). As a positive control, the nonspecific protease thermolysin was inhibited by both EDTA and 1,10-phenanthroline under the same conditions (Fig. 4C).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2023/01/31
Update date2023/03/02
negative Boolean valuefalse
Feature(s) for interactor Ahis tag:?-?
mutation decreasing interaction:229-229
mutation disrupting interaction:257-257
mutation disrupting interaction:258-258
mutation disrupting interaction:357-357
mutation with no effect:227-227
mutation with no effect:328-328
Feature(s) for interactor Bbinding-associated region:1-169
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AMolecular weight estimation by coomasie staining
Participant identification method for interactor BMolecular weight estimation by coomasie staining