| Unique identifier for interactor A | uniprotkb:P37840 |
| Unique identifier for interactor B | uniprotkb:P0CG48 |
| Alternative identifier for interactor A | intact:EBI-985879 uniprotkb:A8K2A4 ensembl:ENSP00000338345.3 ensembl:ENSP00000378437.1 ensembl:ENSP00000378442.4 ensembl:ENSP00000422238.1 ensembl:ENSP00000426955.1 ensembl:ENSP00000500990.1 uniprotkb:Q13701 uniprotkb:Q4JHI3 uniprotkb:Q6IAU6 |
| Alternative identifier for interactor B | intact:EBI-3390054 uniprotkb:Q9BWD6 uniprotkb:P02249 uniprotkb:Q8WYN8 uniprotkb:Q91887 uniprotkb:Q9UPK7 uniprotkb:P62988 uniprotkb:P02250 uniprotkb:Q9UEK8 uniprotkb:Q6LDU5 uniprotkb:Q91888 uniprotkb:Q6LBL4 uniprotkb:Q9UEF2 uniprotkb:Q29120 uniprotkb:P02248 uniprotkb:Q9BX98 uniprotkb:Q9UEG1 ensembl:ENSP00000344818.5 ensembl:ENSP00000441543.1 |
| Aliases for A | psi-mi:syua_human(display_long) uniprotkb:Non-A beta component of AD amyloid(gene name synonym) uniprotkb:Non-A4 component of amyloid precursor(gene name synonym) uniprotkb:SNCA(gene name) psi-mi:SNCA(display_short) uniprotkb:NACP(gene name synonym) uniprotkb:PARK1(gene name synonym) |
| Aliases for B | psi-mi:ubc_human(display_long) uniprotkb:UBC(gene name) psi-mi:UBC(display_short) |
| Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
| First author | Kalia et al. (2011) |
| Identifier of the publication | imex:IM-29687 pubmed:21358815 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-26967257 imex:IM-29687-5 |
| Confidence score | intact-miscore:0.52 |
| Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:fig. 2e variable_condition:To generate the synKR-luc1 and synKR-luc2 constructs, a coding sequence was designed in which all lysines in human full-length wild-type a-syn were substituted with arginine using codons to minimize sequence differences between wild-type and mutant. comment:"\"The mutant synKR-luc1, like wild-type syn-luc1, could be immunoprecipitated by anti-luc antibodies and was detected on Western blot with an anti-a-syn antibody (H3C) which binds to an epitope that contains no lysines within the carboxyl terminal region of a-syn. We discovered that one of the three bands from syn-luc1 immunoprecipitates detected by anti-HA antibodies was not present in synKR-luc1 immunoprecipitates, indicating that this band corresponds to a ubiquitinylated form of a-syn in cells (Fig. 2B).\"" dataset:Brain Disease - Neurological Diseases & Disorders full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-h4) taxid:9606(Homo sapiens H4 neurogioma cell) |
| Parameters of the interaction | - |
| Creation date | 2021/04/06 |
| Update date | 2021/04/29 |
| negative Boolean value | false |
| Feature(s) for interactor A | gaussia-n:c-c |
| Feature(s) for interactor B | ha tag:n-n |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Anti tag western blot |
| Participant identification method for interactor B | Anti tag western blot |