| Unique identifier for interactor A | uniprotkb:Q96NR3 |
| Unique identifier for interactor B | uniprotkb:P26196 |
| Alternative identifier for interactor A | intact:EBI-40253628 uniprotkb:B4DQH0 uniprotkb:Q0IJ60 uniprotkb:Q6P6B8 ensembl:ENSP00000368666.4 |
| Alternative identifier for interactor B | intact:EBI-351257 uniprotkb:Q5D048 ensembl:ENSP00000433704.1 ensembl:ENSP00000442266.1 ensembl:ENSP00000478754.1 |
| Aliases for A | psi-mi:pthd1_human(display_long) uniprotkb:PTCHD1(gene name) psi-mi:PTCHD1(display_short) |
| Aliases for B | psi-mi:ddx6_human(display_long) uniprotkb:DDX6(gene name) psi-mi:DDX6(display_short) uniprotkb:HLR2(gene name synonym) uniprotkb:RCK(gene name synonym) uniprotkb:DEAD box protein 6(gene name synonym) uniprotkb:ATP-dependent RNA helicase p54(gene name synonym) uniprotkb:Oncogene RCK(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
| First author | Hiltunen et al. (2023) |
| Identifier of the publication | pubmed:36769003 imex:IM-29683 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0914"(association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-40253677 imex:IM-29683-1 |
| Confidence score | intact-miscore:0.35 |
| Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:T1 comment:"\"We performed a co-immunoprecipitation assay of PTCHD1 in HEK293 cells, followed by identifying protein–protein interactions from the lysate by mass spectrometry. Ninety-five proteins, with a 10 lgP score above a set threshold and ID’d with at least three unique peptides, were found to co-immunoprecipitate with PTCHD1 (Supplementary Table S2). To identify PTCHD1-specific interactors, we compared the hits from mass spectrometry against those immunoprecipitated by the highly similar proteins PTCH1 and PTCH2. After removing common hits, we identified 13 PTCHD1-specific protein–protein interactors (Table 1).\"" curation depth:imex curation dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\"" full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-293) taxid:9606(Homo sapiens HEK293 embryonic kidney cell) |
| Parameters of the interaction | - |
| Creation date | 2023/02/24 |
| Update date | 2024/11/28 |
| negative Boolean value | false |
| Feature(s) for interactor A | tandem tag:c-c |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Identification by mass spectrometry |
| Participant identification method for interactor B | Identification by mass spectrometry |