Curation Details
Interaction ID: IM-29676-229

Unique identifier for interactor Auniprotkb:P13569
Unique identifier for interactor Buniprotkb:P37059
Alternative identifier for interactor Aintact:EBI-349854
ensembl:ENSP00000003084.6
uniprotkb:Q20BG8
uniprotkb:Q20BH2
uniprotkb:Q2I0A1
uniprotkb:Q2I102
Alternative identifier for interactor Bintact:EBI-11724790
ensembl:ENSP00000199936.4
uniprotkb:B2R7T4
Aliases for Apsi-mi:cftr_human(display_long)
uniprotkb:CFTR(gene name)
psi-mi:CFTR(display_short)
uniprotkb:ABCC7(gene name synonym)
uniprotkb:cAMP-dependent chloride channel(gene name synonym)
uniprotkb:ATP-binding cassette sub-family C member 7(gene name synonym)
uniprotkb:Channel conductance-controlling ATPase(gene name synonym)
Aliases for Bpsi-mi:dhb2_human(display_long)
uniprotkb:HSD17B2(gene name)
psi-mi:HSD17B2(display_short)
uniprotkb:EDH17B2(gene name synonym)
uniprotkb:SDR9C2(gene name synonym)
uniprotkb:20 alpha-hydroxysteroid dehydrogenase(gene name synonym)
uniprotkb:E2DH(gene name synonym)
uniprotkb:Microsomal 17-beta-hydroxysteroid dehydrogenase(gene name synonym)
uniprotkb:Short chain dehydrogenase/reductase family 9C member 2(gene name synonym)
uniprotkb:Testosterone 17-beta-dehydrogenase(gene name synonym)
uniprotkb:Estradiol 17-beta-dehydrogenase 2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0112"(ubiquitin reconstruction)
First authorLim et al. (2022)
Identifier of the publicationpubmed:35156780
imex:IM-29676
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-40229539
imex:IM-29676-229
Confidence scoreintact-miscore:0.37
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:Dataset EV2
dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2022/02/16
Update date2023/02/07
negative Boolean valuefalse
Feature(s) for interactor Acub:c-c
fusion protein:c-c
fluorescent protein tag:c-c
mutation:508-508
Feature(s) for interactor Bnub:n-n
mcherry fluorescent protein tag:c-c
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification