Curation Details
Interaction ID: IM-29676-185

Unique identifier for interactor Auniprotkb:P13569
Unique identifier for interactor Buniprotkb:O00299
Alternative identifier for interactor Aintact:EBI-349854
uniprotkb:Q20BG8
uniprotkb:Q20BH2
uniprotkb:Q2I0A1
uniprotkb:Q2I102
ensembl:ENSP00000003084.6
Alternative identifier for interactor Bintact:EBI-347404
uniprotkb:Q15089
uniprotkb:Q502X1
ensembl:ENSP00000364934.2
ensembl:ENSP00000364935.2
ensembl:ENSP00000364940.3
ensembl:ENSP00000372896.2
ensembl:ENSP00000372897.2
ensembl:ENSP00000379229.1
ensembl:ENSP00000382926.3
ensembl:ENSP00000382931.1
ensembl:ENSP00000391395.1
ensembl:ENSP00000398056.2
ensembl:ENSP00000400280.1
ensembl:ENSP00000400532.1
ensembl:ENSP00000401292.2
ensembl:ENSP00000404037.1
ensembl:ENSP00000404589.1
ensembl:ENSP00000406088.1
ensembl:ENSP00000406335.2
ensembl:ENSP00000406968.1
ensembl:ENSP00000407429.2
ensembl:ENSP00000407791.2
ensembl:ENSP00000408094.1
ensembl:ENSP00000408357.1
ensembl:ENSP00000409247.1
ensembl:ENSP00000409979.1
ensembl:ENSP00000410965.1
ensembl:ENSP00000412217.1
ensembl:ENSP00000413330.1
ensembl:ENSP00000416211.1
ensembl:ENSP00000477623.1
ensembl:ENSP00000478930.1
ensembl:ENSP00000479501.1
ensembl:ENSP00000479808.1
ensembl:ENSP00000480256.1
ensembl:ENSP00000482255.1
ensembl:ENSP00000484581.1
Aliases for Apsi-mi:cftr_human(display_long)
uniprotkb:CFTR(gene name)
psi-mi:CFTR(display_short)
uniprotkb:ABCC7(gene name synonym)
uniprotkb:cAMP-dependent chloride channel(gene name synonym)
uniprotkb:ATP-binding cassette sub-family C member 7(gene name synonym)
uniprotkb:Channel conductance-controlling ATPase(gene name synonym)
Aliases for Bpsi-mi:clic1_human(display_long)
uniprotkb:CLIC1(gene name)
psi-mi:CLIC1(display_short)
uniprotkb:NCC27(gene name synonym)
uniprotkb:Nuclear chloride ion channel 27(gene name synonym)
uniprotkb:Chloride channel ABP(gene name synonym)
uniprotkb:Regulatory nuclear chloride ion channel protein(gene name synonym)
uniprotkb:G6(gene name synonym)
uniprotkb:Glutaredoxin-like oxidoreductase CLIC1(gene name synonym)
uniprotkb:Glutathione-dependent dehydroascorbate reductase CLIC1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0112"(ubiquitin reconstruction)
First authorLim et al. (2022)
Identifier of the publicationpubmed:35156780
imex:IM-29676
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-40218286
imex:IM-29676-185
Confidence scoreintact-miscore:0.79
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:Dataset EV2
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2022/02/16
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Acub:c-c
fusion protein:c-c
fluorescent protein tag:c-c
mutation:508-508
Feature(s) for interactor Bnub:n-n
mcherry fluorescent protein tag:c-c
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification