| Unique identifier for interactor A | uniprotkb:P46935 |
| Unique identifier for interactor B | uniprotkb:Q60760 |
| Alternative identifier for interactor A | intact:EBI-773516 uniprotkb:O08758 uniprotkb:Q3UZI2 uniprotkb:Q8BGB3 ensembl:ENSMUSP00000034740.8 |
| Alternative identifier for interactor B | intact:EBI-861810 uniprotkb:O35352 uniprotkb:Q7TSA4 uniprotkb:Q8BSH4 uniprotkb:Q8BSS5 uniprotkb:Q91WC5 uniprotkb:Q3TQ71 |
| Aliases for A | psi-mi:nedd4_mouse(display_long) uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym) uniprotkb:Nedd4(gene name) psi-mi:Nedd4(display_short) uniprotkb:Kiaa0093(gene name synonym) uniprotkb:Nedd-4(gene name synonym) uniprotkb:Nedd4a(gene name synonym) uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) uniprotkb:Nedd4-1(gene name synonym) uniprotkb:Rpf1(gene name synonym) |
| Aliases for B | psi-mi:grb10_mouse(display_long) uniprotkb:GRB10 adapter protein(gene name synonym) uniprotkb:Grb10(gene name) psi-mi:Grb10(display_short) uniprotkb:Meg1(gene name synonym) uniprotkb:Maternally expressed gene 1 protein(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0018"(two hybrid) |
| First author | Morrione et al. (1999) |
| Identifier of the publication | pubmed:10446181 mint:MINT-5211739 imex:IM-29671 |
| NCBI Taxonomy identifier for interactor A | taxid:10090(mouse) taxid:10090(Mus musculus) |
| NCBI Taxonomy identifier for interactor B | taxid:10090(mouse) taxid:10090(Mus musculus) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-861860 imex:IM-29671-7 |
| Confidence score | author score:++++ intact-miscore:0.58 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:Fig 1 comment:Both BPS and SH2 domains of mGrb10 can independently bind Nedd4, but the SH2 domain seems to bind more strongly. curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:4932(yeasx) taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") |
| Parameters of the interaction | - |
| Creation date | 2001/03/05 |
| Update date | 2026/01/11 |
| negative Boolean value | false |
| Feature(s) for interactor A | sufficient binding region:65-237 |
| Feature(s) for interactor B | sufficient binding region:518-621(IPR000980) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |